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Taha Merghoub

  1. "Molecular Pharmacology and Chemistry Program Faculty"
Formats
  1. Journal Article (14)
  2. Meeting Abstract (11)
Groups
  1. Department of Medicine (25)
  2. GSK Faculty (25)
  3. Melanoma and Immunotherapeutics Service (25)
  4. Molecular Pharmacology and Chemistry Program Faculty (25)
  5. Sloan Kettering Institute Faculty (25)
  6. Solid Tumor Oncology Division (25)

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People
  1. Jedd Wolchok (17)
  2. Neal Rosen (13)
  3. Ronald Blasberg (8)
  4. Sadna Budhu (7)
  5. David Solit (6)
  6. Inna Serganova (6)

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Years
  1. 2023 (2)
  2. 2022 (4)
  3. 2021 (3)
  4. 2020 (4)
  5. 2019 (1)
  6. 2017 (2)

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Publications
  1. Cancer Research (5)
  2. Journal for ImmunoTherapy of Cancer (4)
  3. Cancer Immunology Research (2)
  4. Nature (2)
  5. Cancer Cell (1)
  6. Cancer Discovery (1)

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Publishers
  1. American Association for Cancer Research (8)
  2. Biomed Central Ltd (4)
  3. Nature Publishing Group (3)
  4. Cell Press (2)
  5. American Society of Clinical Oncology (1)
  6. Elsevier Science, Inc. (1)

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Results (25)

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  • Combining a novel dual RAF/MEK inhibitor with immunomodulation to promote an anti-tumor response
    Meeting Abstract

    Dong, L.; Choi, H.; Budhu, S.; Mehanna, N.; Falik, N.; Rosen, N.; Merghoub, T.; Wolchok, J. D.
    Journal of Immunology (2020)

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  • CTLA-4 blockade drives loss of regulatory T cell functional stability in glycolysis defective tumors
    Meeting Abstract

    Zappasodi, R.; Serganova, I.; Cohen, I.; Maeda, M.; Shindo, M.; Senbabaoglu, Y.; Leftin, A.; Maniyar, R.; Verma, S.; Lubin, M.; more...
    Cancer Research (2020)

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  • Leveraging systematic functional analysis to benchmark an in silico framework distinguishes driver from passenger MEK mutants in cancer
    Journal Article

    Hanrahan, A. J.; Sylvester, B. E.; Chang, M. T.; Elzein, A.; Gao, J.; Han, W.; Liu, Y.; Xu, D.; Gao, S. P.; Gorelick, A. N.; more...
    Cancer Research (2020)

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  • Immuno-PET imaging of activation markers on antigen-specific CD4 T cells in a mouse model of melanoma
    Meeting Abstract

    Krebs, S.; Carter, L.; Hirschhorn-Cymerman, D.; Wolchok, J.; Merghoub, T.; Schoder, H.; Larson, S.
    Journal of Nuclear Medicine (2019)

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  • PTEN loss-of-function alterations are associated with intrinsic resistance to BRAF inhibitors in metastatic melanoma
    Journal Article

    Catalanotti, F.; Cheng, D. T.; Shoushtari, A. N.; Johnson, D. B.; Panageas, K. S.; Momtaz, P.; Higham, C.; Won, H. H.; Harding, J. J.; Merghoub, T.; more...
    JCO Precision Oncology (2017)

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  • Phenformin enhances the efficacy of ERK inhibition in NF1-mutant melanoma
    Journal Article

    Trousil, S.; Chen, S.; Mu, C.; Shaw, F. M.; Yao, Z.; Ran, Y.; Shakuntala, T.; Merghoub, T.; Manstein, D.; Rosen, N.; more...
    Journal of Investigative Dermatology (2017)

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  • Kinase regulation of human MHC class i molecule expression on cancer cells
    Journal Article

    Brea, E. J.; Oh, C. Y.; Manchado, E.; Budhu, S.; Gejman, R. S.; Mo, G.; Mondello, P.; Han, J. E.; Jarvis, C. A.; Ulmert, D.; more...
    Cancer Immunology Research (2016)

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  • A retrospective evaluation of vemurafenib as treatment for BRAF-mutant melanoma brain metastases
    Journal Article

    Harding, J. J.; Catalanotti, F.; Munhoz, R. R.; Cheng, D. T.; Yaqubie, A.; Kelly, N.; McDermott, G. C.; Kersellius, R.; Merghoub, T.; Lacouture, M. E.; more...
    The Oncologist (2015)

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  • Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor
    Journal Article

    Callahan, M. K.; Masters, G.; Pratilas, C. A.; Ariyan, C.; Katz, J.; Kitano, S.; Russell, V.; Gordon, R. A.; Vyas, S.; Yuan, J. D.; more...
    Cancer Immunology Research (2014)

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  • Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence
    Journal Article

    Nissan, M. H.; Pratilas, C. A.; Jones, A. M.; Ramirez, R.; Won, H.; Liu, C.; Tiwari, S.; Kong, L.; Hanrahan, A. J.; Yao, Z.; more...
    Cancer Research (2014)

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