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Taha Merghoub

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Journal Article (35)
  2. Meeting Abstract (13)
Groups
  1. Department of Medicine (48)
  2. GSK Faculty (48)
  3. Human Oncology and Pathogenesis Program (48)
  4. Melanoma and Immunotherapeutics Service (48)
  5. Solid Tumor Oncology Division (48)
  6. Department of Pathology and Laboratory Medicine (34)

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People
  1. Jedd Wolchok (35)
  2. Alan Houghton (15)
  3. David Solit (14)
  4. Gabrielle Rizzuto (14)
  5. Vinod Balachandran (12)
  6. Cailian Liu (11)

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Years
  1. 2023 (4)
  2. 2022 (6)
  3. 2021 (3)
  4. 2020 (5)
  5. 2019 (3)
  6. 2018 (1)

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Publications
  1. Journal of Clinical Oncology (8)
  2. Cancer Research (6)
  3. Nature (6)
  4. Cancer Cell (3)
  5. Journal for ImmunoTherapy of Cancer (3)
  6. Journal of Experimental Medicine (3)

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Publishers
  1. American Society of Clinical Oncology (9)
  2. American Association for Cancer Research (8)
  3. Nature Publishing Group (8)
  4. Cell Press (5)
  5. Biomed Central Ltd (3)
  6. Public Library of Science (3)

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Results (48)

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  • Early predictors of benefit to dual anti-PD1/HER2 inhibition: Biomarker analysis from phase 2 trial of pembrolizumab/trastuzumab in HER2-positive metastatic esophagogastric (mEG) cancer
    Meeting Abstract

    Maron, S. B.; Chatila, W. K.; Walch, H. S.; Ptashkin, R.; Sabwa, S.; Ling, L.; Nagy, R.; Simmons, M.; Do, R. K. G.; Paroder, V.; more...
    Journal of Clinical Oncology (2021)

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  • Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness
    Journal Article

    Hirschhorn, D.; Betof Warner, A.; Maniyar, R.; Chow, A.; Mangarin, L. M. B.; Cohen, A. D.; Hamadene, L.; Rizzuto, G. A.; Budhu, S.; Suek, N.; more...
    JCI Insight (2021)

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  • Tim-4(+) cavity-resident macrophages impair anti-tumor CD8(+) T cell immunity
    Journal Article

    Chow, A.; Schad, S.; Green, M. D.; Hellmann, M. D.; Allaj, V.; Ceglia, N.; Zago, G.; Shah, N. S.; Sharma, S. K.; Mattar, M.; more...
    Cancer Cell (2021)

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  • Tim-4(+) resident macrophages impair anti-tumor immunity in the serous body cavities by sequestering viable and cytotoxic CD8(+) T cells expressing high levels of phosphatidylserine
    Meeting Abstract

    Chow, A.; Schad, S.; Green, M.; Hellmann, M.; Ceglia, N.; Allaj, V.; Zago, G.; Shah, N.; Sharma, S.; Mattar, M.; more...
    Journal for ImmunoTherapy of Cancer (2020)

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  • Pembrolizumab with trastuzumab and chemotherapy (PTC) in HER2-positive metastatic esophagogastric cancer (mEG): Plasma and tumor-based biomarker analysis
    Meeting Abstract

    Maron, S. B.; Chatila, W. K.; Millang, B. M.; Sabwa, S.; Chou, J. F.; Ling, L.; Nagy, R.; Simmons, M.; Do, R. K. G.; Paroder, V.; more...
    Journal of Clinical Oncology (2020)

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  • Leveraging systematic functional analysis to benchmark an in silico framework distinguishes driver from passenger MEK mutants in cancer
    Journal Article

    Hanrahan, A. J.; Sylvester, B. E.; Chang, M. T.; Elzein, A.; Gao, J.; Han, W.; Liu, Y.; Xu, D.; Gao, S. P.; Gorelick, A. N.; more...
    Cancer Research (2020)

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  • iNOS regulates the therapeutic response of pancreatic cancer cells to radiotherapy
    Journal Article

    Pereira, P. M. R.; Edwards, K. J.; Mandleywala, K.; Carter, L. M.; Escorcia, F. E.; Campesato, L. F.; Cornejo, M.; Abma, L.; Mohsen, A. A.; Iacobuzio-Donahue, C. A.; more...
    Cancer Research (2020)

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  • ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity
    Journal Article

    Moral, J. A.; Leung, J.; Rojas, L. A.; Ruan, J.; Zhao, J.; Sethna, Z.; Ramnarain, A.; Gasmi, B.; Gururajan, M.; Redmond, D.; more...
    Nature (2020)

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  • Tissue-specific innate lymphoid cells are novel targets for pancreatic cancer immunotherapy
    Meeting Abstract

    Leung, J.; Rojas, L. A.; Ruan, J.; Zhao, J.; Gasmi, B.; Sethna, Z.; Ramnarain, A.; Bhanot, U.; Askan, G.; Gururajan, M.; more...
    Cancer Research (2019)

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  • In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors
    Journal Article

    Khalil, D. N.; Suek, N.; Campesato, L. F.; Budhu, S.; Redmond, D.; Samstein, R. M.; Krishna, C.; Panageas, K. S.; Capanu, M.; Houghton, S.; more...
    Journal of Clinical Investigation (2019)

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