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Renier J Brentjens

  1. "Dayenne van Leeuwen"
Formats
  1. Journal Article (6)
  2. Meeting Abstract (4)
Groups
  1. Adult Leukemia (10)
  2. Center for Hematologic Malignancies (10)
  3. Department of Medicine (10)
  4. GSK Faculty (10)
  5. Hematologic Malignancies Research (10)
  6. Hematologic Malignancies, Division of (10)

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People
  1. Dayenne van Leeuwen (10)
  2. Terence Purdon (10)
  3. Hollie Pegram (6)
  4. Oladapo Yeku (5)
  5. Kevin Curran (4)
  6. Sarwish Rafiq (4)

More People

Years
  1. 2019 (2)
  2. 2018 (4)
  3. 2017 (1)
  4. 2016 (1)
  5. 2015 (2)
Publications
  1. Blood (2)
  2. Molecular Therapy (2)
  3. Cancer Cell (1)
  4. Cancer Research (1)
  5. Cell Reports (1)
  6. JCI Insight (1)

More Publications

Publishers
  1. Nature Publishing Group (4)
  2. American Society of Hematology (2)
  3. Cell Press (2)
  4. Amer Soc Clinical Investigation Inc (1)
  5. American Association for Cancer Research (1)

Results (10)

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  • Safety and tolerability of conditioning chemotherapy followed by CD19-targeted CAR T cells for relapsed/refractory CLL
    Journal Article

    Geyer, M. B.; Riviere, I.; Senechal, B.; Wang, X.; Wang, Y.; Purdon, T. J.; Hsu, M.; Devlin, S. M.; Palomba, M. L.; Halton, E.; more...
    JCI Insight (2019)

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  • CD40 ligand-modified chimeric antigen receptor T cells enhance antitumor function by eliciting an endogenous antitumor response
    Journal Article

    Kuhn, N. F.; Purdon, T. J.; van Leeuwen, D. G.; Lopez, A. V.; Curran, K. J.; Daniyan, A. F.; Brentjens, R. J.
    Cancer Cell (2019)

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  • CAR T cells secreting an immune checkpoint blockade scFv have enhanced anti-tumor efficacy
    Meeting Abstract

    Rafiq, S.; Yeku, O.; Jackson, H.; Purdon, T.; van Leeuwen, D.; Yan, S.; Wang, P.; Xiang, J.; Liu, C.; Seshan, V.; more...
    Cancer Research (2018)

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  • Targeted delivery of a PD-1-blocking scFV by CAR-T cells enhances anti-tumor efficacy in vivo
    Journal Article

    Rafiq, S.; Yeku, O. O.; Jackson, H. J.; Purdon, T. J.; van Leeuwen, D. G.; Drakes, D. J.; Song, M.; Miele, M. M.; Li, Z.; Wang, P.; more...
    Nature Biotechnology (2018)

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  • CAR T cells secreting an immune checkpoint blockade scFv have enhanced anti-tumor efficacy
    Meeting Abstract

    Rafiq, S.; Yeku, O.; Jackson, H.; Purdon, T.; van Leeuwen, D.; Yan, S.; Wang, P.; Xiang, J.; Liu, C.; Brentjens, R.
    Molecular Therapy (2018)

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  • Engineered tumor-targeted T cells mediate enhanced anti-tumor efficacy both directly and through activation of the endogenous immune system
    Journal Article

    Avanzi, M. P.; Yeku, O.; Li, X.; Wijewarnasuriya, D. P.; van Leeuwen, D. G.; Cheung, K.; Park, H.; Purdon, T. J.; Daniyan, A. F.; Spitzer, M. H.; more...
    Cell Reports (2018)

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  • Enhancing CAR T cell anti-tumor efficacy through secreted single chain variable fragment (scFv) immune checkpoint blockade
    Meeting Abstract

    Rafiq, S.; Jackson, H. J.; Yeku, O.; Purdon, T. J.; van Leeuwen, D. G.; Curran, K. J.; Ahmed, R. N.; Cullen, G. D.; Yan, S.; Wang, P.; more...
    Blood (2017)

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  • IL-18 secreting CAR T cells enhance cell persistence, induce prolonged B cell aplasia and eradicate CD19+ tumor cells without need for prior conditioning
    Meeting Abstract

    Avanzi, M. P.; van Leeuwen, D. G.; Li, X.; Cheung, K.; Park, H.; Purdon, T. J.; Brentjens, R. J.
    Blood (2016)

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  • Enhancing antitumor efficacy of chimeric antigen receptor T cells through constitutive CD40L expression
    Journal Article

    Curran, K. J.; Seinstra, B. A.; Nikhamin, Y.; Yeh, R.; Usachenko, Y.; van Leeuwen, D. G.; Purdon, T.; Pegram, H. J.; Brentjens, R. J.
    Molecular Therapy (2015)

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  • IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia
    Journal Article

    Pegram, H. J.; Purdon, T. J.; van Leeuwen, D. G.; Curran, K. J.; Giralt, S. A.; Barker, J. N.; Brentjens, R. J.
    Leukemia (2015)

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