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Renier J Brentjens

  1. "Sloan Kettering Institute Postdocs"
Formats
  1. Journal Article (31)
  2. Meeting Abstract (23)
  3. Review (1)
Groups
  1. Adult Leukemia (55)
  2. Center for Hematologic Malignancies (55)
  3. Department of Medicine (55)
  4. GSK Faculty (55)
  5. Hematologic Malignancies Research (55)
  6. Hematologic Malignancies, Division of (55)

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People
  1. Terence Purdon (23)
  2. Hollie Pegram (19)
  3. Sarwish Rafiq (15)
  4. Jae Park (12)
  5. Isabelle Riviere (11)
  6. Kevin Curran (10)

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Years
  1. 2025 (1)
  2. 2022 (1)
  3. 2021 (4)
  4. 2020 (8)
  5. 2019 (4)
  6. 2018 (9)

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Publications
  1. Blood (15)
  2. Molecular Therapy (5)
  3. Journal of Clinical Oncology (3)
  4. Bone Marrow Transplantation (2)
  5. Cancer Discovery (2)
  6. Cancer Research (2)

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Publishers
  1. American Society of Hematology (16)
  2. Nature Publishing Group (14)
  3. American Association for Cancer Research (6)
  4. American Society of Clinical Oncology (3)
  5. Cell Press (3)
  6. Elsevier Inc. (3)

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Results (55)

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  • Phase I trial of MCARH109, a G protein-coupled receptor class C group 5 member D (GPRC5D)-targeted chimeric antigen receptor T-cell therapy for multiple myeloma: An updated analysis
    Journal Article

    Jurgens, E. M.; Firestone, R. S.; Chaudhari, J.; Hosszu, K.; Devlin, S. M.; Shah, U. A.; Landa, J.; McAvoy, D. P.; Lesokhin, A. M.; Korde, N.; more...
    Journal of Clinical Oncology (2025)

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  • Engineering CAR-T cells to activate small-molecule drugs in situ
    Journal Article

    Gardner, T. J.; Lee, J. P.; Bourne, C. M.; Wijewarnasuriya, D.; Kinarivala, N.; Kurtz, K. G.; Corless, B. C.; Dacek, M. M.; Chang, A. Y.; Mo, G.; more...
    Nature Chemical Biology (2022)

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  • Phase I first-in-class trial of MCARH109, a G protein coupled receptor class C group 5 member D (GPRC5D) targeted CAR T cell therapy in patients with relapsed or refractory multiple myeloma
    Meeting Abstract

    Mailankody, S.; Diamonte, C.; Fitzgerald, L.; Kane, P.; Wang, X.; Sikder, D. S.; Senechal, B.; Bermudez, V. P.; Frias, D.; Morgan, J.; more...
    Blood (2021)

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  • Human cytomegalovirus expands a CD8(+) T cell population with loss of BCL11B expression and gain of NK cell identity
    Journal Article

    Sottile, R.; Panjwani, M. K.; Lau, C. M.; Daniyan, A. F.; Tanaka, K.; Barker, J. N.; Brentjens, R. J.; Sun, J. C.; Le Luduec, J. B.; Hsu, K. C.
    Science Immunology (2021)

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  • Decreased neuroprotective analytes on day of infusion of chimeric antigen receptor (CAR) T cells are associated with neurotoxicity
    Meeting Abstract

    Lakkaraja, M.; Hosszu, K.; McAvoy, D.; Mauguen, A.; Purdon, T. J.; Khakoo, Y.; Santomasso, B. D.; Riviere, I.; Sadelain, M.; Curran, K. J.; more...
    Bone Marrow Transplantation (2021)

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  • Predictors for neurotoxicity on day of infusion of chimeric antigen receptor (CAR) T cells using discovery proteomics platform
    Meeting Abstract

    Lakkaraja, M.; Hosszu, K.; McAvoy, D.; Mauguen, A.; Purdon, T. J.; Auchincloss, T.; Klein, E.; Khakoo, Y.; Santomasso, B.; Senechal, B.; more...
    Cytotherapy (2021)

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  • Defining an optimal dual-targeted CAR T-cell therapy approach simultaneously targeting BCMA and GPRC5D to prevent BCMA escape– Driven relapse in multiple myeloma
    Journal Article

    de Larrea, C. F.; Staehr, M.; Lopez, A. V.; Ng, K. Y.; Chen, Y.; Godfrey, W. D.; Purdon, T. J.; Ponomarev, V.; Wendel, H. G.; Brentjens, R. J.; more...
    Blood Cancer Discovery (2020)

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  • A phase I study of CD19-targeted 19(T2)28z1xx CAR T cells in adult patients with relapsed or refractory B-cell malignancies
    Meeting Abstract

    Park, J. H.; Riviere, I.; Sikder, D. S.; Bermudez, V. P.; Senechal, B.; Wang, X.; Auchincloss, T. H.; Diamonte, C.; Halton, E.; Palomba, M. L.; more...
    Blood (2020)

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  • Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages
    Journal Article

    Song, M.; Yeku, O. O.; Rafiq, S.; Purdon, T.; Dong, X.; Zhu, L.; Zhang, T.; Wang, H.; Yu, Z.; Mai, J.; more...
    Nature Communications (2020)

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  • Low toxicity and favorable overall survival in relapsed/refractory B-ALL following CAR T cells and CD34-selected T-cell depleted allogeneic hematopoietic cell transplant
    Journal Article

    Fabrizio, V. A.; Kernan, N. A.; Boulad, F.; Cancio, M.; Allen, J.; Higman, M.; Margossian, S. P.; Mauguen, A.; Prockop, S.; Scaradavou, A.; more...
    Bone Marrow Transplantation (2020)

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