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Andrew C Koff

  1. "Sarcoma Surgeons"
Formats
  1. Journal Article (8)
  2. Meeting Abstract (3)
Groups
  1. GSK Faculty (11)
  2. Molecular Biology Program Faculty (11)
  3. Sarcoma Surgeons (11)
  4. Sloan Kettering Institute Faculty (11)
  5. Surgery (11)
  6. Tow Center for Developmental Oncology (TCDO) (11)

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People
  1. Samuel Singer (11)
  2. Aimee Crago (9)
  3. Mark Dickson (9)
  4. William Tap (9)
  5. Cristina Antonescu (7)
  6. Li-Xuan Qin (6)

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Years
  1. 2024 (1)
  2. 2022 (1)
  3. 2019 (1)
  4. 2018 (3)
  5. 2017 (1)
  6. 2016 (1)

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Publications
  1. Clinical Cancer Research (2)
  2. Nature Communications (2)
  3. American Society of Clinical Oncology Educational Book (1)
  4. Annals of Oncology (1)
  5. Cancer Research (1)
  6. JAMA Oncology (1)

More Publications

Publishers
  1. American Association for Cancer Research (3)
  2. Nature Publishing Group (3)
  3. American Society of Clinical Oncology (2)
  4. American Medical Association (1)
  5. Impact Journals (1)
  6. Oxford University Press (1)

Results (11)

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  • Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma
    Journal Article

    Gleason, C. E.; Dickson, M. A.; Klein, M. E.; Antonescu, C. R.; Gularte-MeĢrida, R.; Benitez, M.; Delgado, J. I.; Kataru, R. P.; Tan, M. W. Y.; Bradic, M.; more...
    Clinical Cancer Research (2024)

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  • Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma
    Journal Article

    D'Angelo, S. P.; Richards, A. L.; Conley, A. P.; Woo, H. J.; Dickson, M. A.; Gounder, M.; Kelly, C.; Keohan, M. L.; Movva, S.; Thornton, K.; more...
    Nature Communications (2022)

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  • Phase 2 study of the CDK4 inhibitor abemaciclib in dedifferentiated liposarcoma
    Meeting Abstract

    Dickson, M. A.; Koff, A.; D'Angelo, S. P.; Gounder, M. M.; Keohan, M. L.; Kelly, C. M.; Chi, P.; Antonescu, C. R.; Landa, J.; Qin, L. X.; more...
    Journal of Clinical Oncology (2019)

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  • PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence
    Journal Article

    Klein, M. E.; Dickson, M. A.; Antonescu, C.; Qin, L. X.; Dooley, S. J.; Barlas, A.; Manova, K.; Schwartz, G. K.; Crago, A. M.; Singer, S.; more...
    Oncogene (2018)

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  • Senescence after growth arrest: A mechanism by which CDK4/6 inhibitors can mediate their activity suppressing tumor progression
    Meeting Abstract

    Koff, A.; Klein, M. E.; Dickson, M. A.; Antonescu, C.; Qin, L. X.; Dooley, S. J.; Schwartz, G.; Crago, A. M.; Singer, S.; Tap, W. D.
    Annals of Oncology (2018)

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  • CDK4 inhibition and senescence: Pathway understanding leads to rational drug combinations
    Meeting Abstract

    Klein, M. E.; Kovatcheva, M.; Dickson, M. A.; Liu, D.; Crago, A. M.; Schwartz, G. K.; Tap, W. D.; Singer, S.; Koff, A.
    Clinical Cancer Research (2018)

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  • ATRX is a regulator of therapy induced senescence in human cells
    Journal Article

    Kovatcheva, M.; Liao, W.; Klein, M. E.; Robine, N.; Geiger, H.; Crago, A. M.; Dickson, M. A.; Tap, W. D.; Singer, S.; Koff, A.
    Nature Communications (2017)

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  • Progression-free survival among patients with well-differentiated or dedifferentiated liposarcoma treated with CDK4 inhibitor palbociclib: A phase 2 clinical trial
    Journal Article

    Dickson, M. A.; Schwartz, G. K.; Louise Keohan, M.; D'Angelo, S. P.; Gounder, M. M.; Chi, P.; Antonescu, C. R.; Landa, J.; Qin, L. X.; Crago, A. M.; more...
    JAMA Oncology (2016)

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  • Application of molecular biology to individualize therapy for patients with liposarcoma
    Journal Article

    Abbas Manji, G.; Singer, S.; Koff, A.; Schwartz, G. K.
    American Society of Clinical Oncology Educational Book (2015)

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  • MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition
    Journal Article

    Kovatcheva, M.; Liu, D. D.; Dickson, M. A.; Klein, M. E.; O'Connor, R.; Wilder, F. O.; Socci, N. D.; Tap, W. D.; Schwartz, G. K.; Singer, S.; more...
    Oncotarget (2015)

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