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Andrew C Koff

  1. "Department of Pathology and Laboratory Medicine"
Formats
  1. Journal Article (8)
  2. Meeting Abstract (2)
Groups
  1. Department of Pathology and Laboratory Medicine (10)
  2. GSK Faculty (10)
  3. Molecular Biology Program Faculty (10)
  4. Sloan Kettering Institute Faculty (10)
  5. Department of Medicine (8)
  6. Surgery (8)

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People
  1. Cristina Antonescu (7)
  2. Samuel Singer (7)
  3. Aimee Crago (6)
  4. Li-Xuan Qin (6)
  5. Mark Dickson (6)
  6. William Tap (6)

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Years
  1. 2024 (2)
  2. 2022 (1)
  3. 2019 (1)
  4. 2018 (2)
  5. 2016 (1)
  6. 2010 (1)

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Publications
  1. Annals of Oncology (1)
  2. Cancer Cell (1)
  3. Cancer Research (1)
  4. Clinical Cancer Research (1)
  5. EMBO Journal (1)
  6. JAMA Oncology (1)

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Publishers
  1. American Association for Cancer Research (2)
  2. Nature Publishing Group (2)
  3. American Medical Association (1)
  4. American Society for Microbiology (1)
  5. American Society of Clinical Oncology (1)
  6. Cell Press (1)

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Results (10)

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  • Long-term breast cancer response to CDK4/6 inhibition defined by TP53-mediated geroconversion
    Journal Article

    Kudo, R.; Safonov, A.; Jones, C.; Moiso, E.; Dry, J. R.; Shao, H.; Nag, S.; da Silva, E. M.; Yildirim, S. Y.; Li, Q.; more...
    Cancer Cell (2024)

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  • Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma
    Journal Article

    Gleason, C. E.; Dickson, M. A.; Klein, M. E.; Antonescu, C. R.; Gularte-MeĢrida, R.; Benitez, M.; Delgado, J. I.; Kataru, R. P.; Tan, M. W. Y.; Bradic, M.; more...
    Clinical Cancer Research (2024)

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  • Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma
    Journal Article

    D'Angelo, S. P.; Richards, A. L.; Conley, A. P.; Woo, H. J.; Dickson, M. A.; Gounder, M.; Kelly, C.; Keohan, M. L.; Movva, S.; Thornton, K.; more...
    Nature Communications (2022)

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  • Phase 2 study of the CDK4 inhibitor abemaciclib in dedifferentiated liposarcoma
    Meeting Abstract

    Dickson, M. A.; Koff, A.; D'Angelo, S. P.; Gounder, M. M.; Keohan, M. L.; Kelly, C. M.; Chi, P.; Antonescu, C. R.; Landa, J.; Qin, L. X.; more...
    Journal of Clinical Oncology (2019)

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  • PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence
    Journal Article

    Klein, M. E.; Dickson, M. A.; Antonescu, C.; Qin, L. X.; Dooley, S. J.; Barlas, A.; Manova, K.; Schwartz, G. K.; Crago, A. M.; Singer, S.; more...
    Oncogene (2018)

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  • Senescence after growth arrest: A mechanism by which CDK4/6 inhibitors can mediate their activity suppressing tumor progression
    Meeting Abstract

    Koff, A.; Klein, M. E.; Dickson, M. A.; Antonescu, C.; Qin, L. X.; Dooley, S. J.; Schwartz, G.; Crago, A. M.; Singer, S.; Tap, W. D.
    Annals of Oncology (2018)

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  • Progression-free survival among patients with well-differentiated or dedifferentiated liposarcoma treated with CDK4 inhibitor palbociclib: A phase 2 clinical trial
    Journal Article

    Dickson, M. A.; Schwartz, G. K.; Louise Keohan, M.; D'Angelo, S. P.; Gounder, M. M.; Chi, P.; Antonescu, C. R.; Landa, J.; Qin, L. X.; Crago, A. M.; more...
    JAMA Oncology (2016)

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  • ZIC1 overexpression is oncogenic in liposarcoma
    Journal Article

    Brill, E.; Gobble, R.; Angeles, C.; Lagos-Quintana, M.; Crago, A.; Laxa, B.; Decarolis, P.; Zhang, L.; Antonescu, C.; Socci, N. D.; more...
    Cancer Research (2010)

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  • Somatic cell type specific gene transfer reveals a tumor-promoting function for p21Waf1/Cip1
    Journal Article

    Liu, Y.; Yeh, N.; Zhu, X. H.; Leversha, M.; Cordon-Cardo, C.; Ghossein, R.; Singh, B.; Holland, E.; Koff, A.
    EMBO Journal (2007)

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  • The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2
    Journal Article

    Liu, Y.; Hedvat, C. V.; Mao, S.; Zhu, X. H.; Yao, J.; Nguyen, H.; Koff, A.; Nimer, S. D.
    Molecular and Cellular Biology (2006)

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