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Research Focus

Former Employee. Chemical Biology Program; Research Fellow

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1. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

   Journal Article

   Hur, J. Y.; Frost, G. R.; Wu, X.; Crump, C.; Pan, S. J.; Wong, E.; Barros, M.; Li, T.; Nie, P.; Zhai, Y.; more...
   Nature (2020)

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2. γ-secretase partitioning into lipid bilayers remodels membrane microdomains after direct insertion

   Journal Article

   Barros, M.; Houlihan, W. J.; Paresi, C. J.; Brendel, M.; Rynearson, K. D.; Lee, C. W.; Prikhodko, O.; Cregger, C.; Chang, G.; Wagner, S. L.; more...
   Langmuir (2020)

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3. Substrate interaction inhibits γ-secretase production of amyloid-β peptides

   Research Letter

   Zhao, J.; Xiao, Y.; Liu, X.; Kim, S.; Wu, X.; Barros, M.; Zhuang, R.; Hou, X.; Zhang, Y.; Robakis, N. K.; more...
   Chemical Communications (2020)

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