Synapse - Ira Dunkel

Results (375)

Report on Pediatric Brain Tumor Consortium (PBTC)-029b, a prospective phase 2 clinical trial of selumetinib in treating young patients with recurrent/progressive low-grade glioma: New results on strata 2, 5, and 6 with updated long-term survival outcomes on strata 1, 3, and 4

Meeting Abstract

Fangusaro, J.; Onar-Thomas, A.; Poussaint, T. Y.; Lensing, S.; Ligon, A. H.; Lindeman, N.; Banerjee, A.; Kilburn, L.; Lenzen, A.; Pillay-Smiley, N.; more...
Neuro-Oncology (2024)

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Phase 1 Study of the Cd40 agonistic monoclonal antibody APX005M (sotigalimab) in pediatric, adolescent, and young adult patients with recurrent or progressive CNS tumors and newly diagnosed brain stem glioma: A Pediatric Brain Tumor Consortium study (PBTC-051; NCT03389802)

Meeting Abstract

Lindsay, H. B.; Billups, C.; Baxter, P.; Hwang, E.; Lenzen, A.; MacDonald, T.; Pollack, I. F.; Robison, N.; Vinitsky, A.; Poussaint, T. Y.; more...
Neuro-Oncology (2024)

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Direct patient outreach in pediatric neurooncology to improve access to genomic profiling – The make-an-impact program

Meeting Abstract

Sait, S. F.; O'Donohue, T.; Hill, K.; Stockfish, E.; Giantini-Larsen, A.; Alano, T.; Bale, T.; Rosenblum, M.; Benhamida, J.; Dunkel, I.; more...
Neuro-Oncology (2024)

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Outcome of patients with recurrent medulloblastoma and ependymoma treated with pembrolizumab, an immune checkpoint inhibitor: A Pediatric Brain Tumor Consortium study (PBTC045)

Meeting Abstract

Hwang, E. I.; Kilburn, L. B.; Mitchell, D. A.; Lin, T.; Young-Poussaint, T.; Robinson, G.; Gajjar, A.; Lenzen, A.; Dorris, K.; Robison, N.; more...
Neuro-Oncology (2024)

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Pediatric Brain Tumor Consortium (PBTC)-056: A phase 1 study of the ADAM-10 Inhibitor, INCB007839, in children with recurrent/progressive high-grade gliomas to target microenvironmental neurologin-3

Meeting Abstract

Lenzen, A.; Partap, S.; Billups, C.; Poussaint, T. Y.; Sait, S. F.; Robison, N.; Castellino, C. C.; Felker, J.; Stewart, C.; Fangusaro, J.; more...
Neuro-Oncology (2024)

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Minimally-invasive molecular diagnosis of diffuse leptomeningeal glioneuronal tumor (DLGNT) using cerebrospinal fluid cell-free DNA sequencing in pediatric and young adult patients

Meeting Abstract

Larsen, A. M. G.; Hill, K.; Hickman, R.; Bale, T. A.; Holle, B.; Mellinghoff, I.; Dunkel, I.; Souweidane, M.; Greenfield, J.; Sait, S. F.; more...
Neuro-Oncology (2024)

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Minimally-invasive molecular diagnosis of infiltrating brainstem gliomas through cerebrospinal fluid cell-free DNA sequencing

Meeting Abstract

Hill, K.; Giantini-Larsen, A.; Hickman, R. A.; Holle, B. M.; Ucpinar, B. A.; Alano, T.; Doe-Tetteh, S.; DiNapoli, S.; Riviere-Cazaux, C.; Burns, T. C.; more...
Neuro-Oncology (2024)

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Theranostic intratumoral convection-enhanced delivery of (124)I-omburtamab in patients with diffuse intrinsic pontine glioma: Pharmacokinetics and lesion dosimetry