Synapse - Andrew Kung

Results (97)

A transcripto me-based precision oncology platform for patient-therapy alignment in a diverse set of treatment-resistant malignancies

Journal Article

Mundi, P. S.; Dela Cruz, F. S.; Grunn, A.; Diolaiti, D.; Mauguen, A.; Rainey, A. R.; Guillan, K.; Siddiquee, A.; You, D.; Realubit, R.; more...
Cancer Discovery (2023)

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Clonal evolution during metastatic spread in high-risk neuroblastoma

Journal Article

Gundem, G.; Levine, M. F.; Roberts, S. S.; Cheung, I. Y.; Medina-Martínez, J. S.; Feng, Y.; Arango-Ossa, J. E.; Chadoutaud, L.; Rita, M.; Asimomitis, G.; more...
Nature Genetics (2023)

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Development of a patient-derived xenograft (PDX) modeling program to enable pediatric precision medicine

Meeting Abstract

Dela Cruz, F. S.; McCarter, J. G.; You, D.; Bouvier, N.; Wang, X.; Guillan, K. C.; Siddiquee, A. H.; Souto, K. B.; Li, H.; Gao, T.; more...
Cancer Research (2022)

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A systems biology approach to defining tumor heterogeneity and prognostic and targetable master regulator protein signatures from bulk and single-cell RNAseq in osteosarcoma

Meeting Abstract

Tagore, S.; Pavisic, J.; Griffin, A. T.; Janeway, K.; Kung, A. L.; Dela Cruz, F.; Sweet-Cordero, A.; Behroozfard, I.; Leung, S.; Lee, A.; more...
Cancer Research (2022)

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Targeting of the nuclear export protein XPO1 represents a non-genetically encoded vulnerability in malignant rhabdoid and Wilms tumors

Meeting Abstract

Coutinho, D. F.; Burke, C.; Mundi, P.; Ortiz, M. V.; Vallance, K. L.; Long, M.; Rosales, N.; Ibanez, G.; Marks, L. J.; Diolaiti, D.; more...
Cancer Research (2022)

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Elucidation and pharmacological targeting of master regulator proteins representing mechanistic determinants of breast cancer stem-like tumor initiating cell state

Meeting Abstract

Worley, J.; Ding, H.; Noh, H.; Paull, E.; Griffin, A. T.; Grunn, A.; You, D.; Guillan, K.; Bush, E.; Dalerba, P.; more...
Cancer Research (2022)

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Effects of LSD1 inhibition with Img-7289 on the leukemia initiating cell population with induction of differentiation and cell death in pediatric relapsed/refractory AML

Meeting Abstract

Rosenzweig, J.; Coutinho, D. F.; Long, M.; Souto, K.; Sanchez, G. I.; Fishkin, R.; Guillan, K.; Siddiquee, A.; Calder, P.; You, D.; more...
Blood (2022)

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Unmatched whole-genome sequencing as a clinical tool for hematological neoplasms with significant utility in cases with tumor-in-normal contamination