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Kenneth Offit

  1. "Early Drug Development Service"
Formats
  1. Journal Article (13)
  2. Meeting Abstract (11)
  3. Research Letter (1)
Groups
  1. Clinical Genetics Service (25)
  2. Department of Medicine (25)
  3. Early Drug Development Service (25)
  4. GSK Faculty (25)
  5. Population Sciences Research Program (25)
  6. Solid Tumor Oncology Division (25)

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People
  1. David Hyman (21)
  2. Zsofia Stadler (20)
  3. Mark Robson (19)
  4. Michael Berger (19)
  5. Diana Mandelker (17)
  6. Marc Ladanyi (16)

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Years
  1. 2023 (1)
  2. 2022 (1)
  3. 2021 (1)
  4. 2020 (2)
  5. 2019 (8)
  6. 2018 (2)

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Publications
  1. Journal of Clinical Oncology (6)
  2. Cancer Research (5)
  3. Nature Genetics (3)
  4. JAMA Oncology (2)
  5. JCO Precision Oncology (2)
  6. Breast Cancer Research and Treatment (1)

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Publishers
  1. American Society of Clinical Oncology (8)
  2. American Association for Cancer Research (5)
  3. Nature Publishing Group (5)
  4. American Medical Association (3)
  5. Elsevier Science, Inc. (1)
  6. Ferrata Storti Foundation (1)

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Results (25)

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  • Genomic profiling reveals germline predisposition and homologous recombination deficiency in pancreatic acinar cell carcinoma
    Journal Article

    Mandelker, D.; Marra, A.; Zheng-Lin, B.; Selenica, P.; Blanco-Heredia, J.; Zhu, Y.; Gazzo, A.; Wong, D.; Yelskaya, Z.; Rai, V.; more...
    Journal of Clinical Oncology (2023)

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  • Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies
    Journal Article

    Murciano-Goroff, Y. R.; Schram, A. M.; Rosen, E. Y.; Won, H.; Gong, Y.; Noronha, A. M.; Janjigian, Y. Y.; Stadler, Z. K.; Chang, J. C.; Yang, S. R.; more...
    Nature Communications (2022)

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  • The context-specific role of germline pathogenicity in tumorigenesis
    Journal Article

    Srinivasan, P.; Bandlamudi, C.; Jonsson, P.; Kemel, Y.; Chavan, S. S.; Richards, A. L.; Penson, A. V.; Bielski, C. M.; Fong, C.; Syed, A.; more...
    Nature Genetics (2021)

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  • Oncologic therapy shapes the fitness landscape of clonal hematopoiesis
    Meeting Abstract

    Bolton, K. L.; Ptashkin, R. N.; Gao, T.; Braunstein, L.; Devlin, S. M.; Patel, M.; Berthon, A.; Syed, A.; Yabe, M.; Coombs, C.; more...
    Cancer Research (2020)

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  • Cancer therapy shapes the fitness landscape of clonal hematopoiesis
    Journal Article

    Bolton, K. L.; Ptashkin, R. N.; Gao, T.; Braunstein, L.; Devlin, S. M.; Kelly, D.; Patel, M.; Berthon, A.; Syed, A.; Yabe, M.; more...
    Nature Genetics (2020)

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  • Understanding inherited risk in unselected newly diagnosed patients with endometrial cancer
    Journal Article

    Cadoo, K. A.; Mandelker, D. L.; Mukherjee, S.; Stewart, C.; DeLair, D.; Ravichandran, V.; Srinivasan, P.; Hurley, D.; Kemel, Y.; Arnold, A. G.; more...
    JCO Precision Oncology (2019)

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  • Integrated germline and somatic analysis identifies actionable cancer predisposing germline mutations in 9,734 patients with advanced cancers
    Meeting Abstract

    Jayakumaran, G.; Mandelker, D.; Birsoy, O.; Jairam, S.; Li, Y.; Yang, C.; Somar, J.; Rai, V.; Syed, A.; Benayed, R.; more...
    Journal of Molecular Diagnostics (2019)

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  • BRCA-mediated tumorigenesis is origin and cell-type dependent
    Meeting Abstract

    Jonsson, P.; Cheng, M. L.; Bandlamudi, C.; Srinivasan, P.; Chavan, S. S.; Friedman, N. D.; Rosen, E. Y.; Richards, A. L.; Bouvier, N.; Selcuklu, S. D.; more...
    Cancer Research (2019)

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  • Zygosity, lineage, and penetrance dictate the role of germline pathogenicity in tumorigenesis
    Meeting Abstract

    Bandlamudi, C.; Srinivasan, P.; Jonsson, P.; Kemel, Y. M.; Chavan, S. S.; Richards, A. L.; Penson, A.; Bielski, C. M.; Fong, C.; Syed, A.; more...
    Cancer Research (2019)

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  • Oncologic therapy for solid tumors alters the risk of clonal hematopoiesis
    Meeting Abstract

    Bolton, K.; Ptashkin, R.; Braunstein, L.; Gao, T.; Devlin, S. M.; Kelly, D.; Coombs, C.; Patel, M.; Moarii, M.; Bernard, E.; more...
    Cancer Research (2019)

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