Synapse - Karuna Ganesh

Results (17)

Progressive plasticity during colorectal cancer metastasis

Journal Article

Moorman, A. R.; Benitez, E. K.; Cambuli, F.; Jiang, Q.; Mahmoud, A.; Lumish, M.; Hartner, S.; Balkaran, S.; Bermeo, J.; Asawa, S.; more...
Nature (2025)

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Characteristics of mismatch repair-deficient colon cancer in relation to mismatch repair protein loss, hypermethylation silencing, and constitutional and biallelic somatic mismatch repair gene pathogenic variants

Journal Article

Keshinro, A.; Ganesh, K.; Vanderbilt, C.; Firat, C.; Kim, J. K.; Chen, C. T.; Yaeger, R.; Segal, N. H.; Gonen, M.; Shia, J.; more...
Diseases of the Colon and Rectum (2023)

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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers

Journal Article

Chatila, W. K.; Walch, H.; Hechtman, J. F.; Moyer, S. M.; Sgambati, V.; Faleck, D. M.; Srivastava, A.; Tang, L.; Benhamida, J.; Ismailgeci, D.; more...
Nature Communications (2023)

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Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Journal Article

Nguyen, B.; Fong, C.; Luthra, A.; Smith, S. A.; DiNatale, R. G.; Nandakumar, S.; Walch, H.; Chatila, W. K.; Madupuri, R.; Kundra, R.; more...
Cell (2022)

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A comprehensive comparison of early-onset and average-onset colorectal cancers

Journal Article

Cercek, A.; Chatila, W. K.; Yaeger, R.; Walch, H.; Dos Santos Fernandes, G.; Krishnan, A.; Palmaira, L.; Maio, A.; Kemel, Y.; Srinivasan, P.; more...
JNCI: Journal of the National Cancer Institute (2021)

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Tumor-infiltrating lymphocytes, tumor mutational burden, and genetic alterations in microsatellite unstable, microsatellite stable, or mutant POLE/POLD1 colon cancer

Journal Article

Keshinro, A.; Vanderbilt, C.; Kim, J. K.; Firat, C.; Chen, C. T.; Yaeger, R.; Ganesh, K.; Segal, N. H.; Gonen, M.; Shia, J.; more...
JCO Precision Oncology (2021)

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Phase II single-arm study of durvalumab and tremelimumab with concurrent radiotherapy in patients with mismatch repair-proficient metastatic colorectal cancer

Journal Article

Segal, N. H.; Cercek, A.; Ku, G.; Wu, A. J.; Rimner, A.; Khalil, D. N.; Reidy-Lagunes, D.; Cuaron, J.; Yang, T. J.; Weiser, M. R.; more...
Clinical Cancer Research (2021)

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Characterization and clinical outcomes of DNA mismatch repair-deficient small bowel adenocarcinoma

Journal Article

Latham, A.; Shia, J.; Patel, Z.; Reidy-Lagunes, D. L.; Segal, N. H.; Yaeger, R.; Ganesh, K.; Connell, L.; Kemeny, N. E.; Kelsen, D. P.; more...
Clinical Cancer Research (2021)

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Mismatch repair-deficient rectal cancer and resistance to neoadjuvant chemotherapy

Journal Article

Cercek, A.; Dos Santos Fernandes, G.; Roxburgh, C. S.; Ganesh, K.; Ng, S.; Sanchez-Vega, F.; Yaeger, R.; Segal, N. H.; Reidy-Lagunes, D. L.; Varghese, A. M.; more...
Clinical Cancer Research (2020)

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Coaltered Ras/B-raf and TP53 is associated with extremes of survivorship and distinct patterns of metastasis in patients with metastatic colorectal cancer

Journal Article

Datta, J.; Smith, J. J.; Chatila, W. K.; McAuliffe, J. C.; Kandoth, C.; Vakiani, E.; Frankel, T. L.; Ganesh, K.; Wasserman, I.; Lipsyc-Sharf, M.; more...
Clinical Cancer Research (2020)

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