Synapse - Jason Chang

Results (49)

Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer

Journal Article

Zucker, M.; Perry, M. A.; Gould, S. I.; Elkrief, A.; Safonov, A.; Thummalapalli, R.; Mehine, M.; Chakravarty, D.; Brannon, A. R.; Ladanyi, M.; more...
Cell (2025)

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Chromothripsis-mediated small cell lung carcinoma

Journal Article

Rekhtman, N.; Tischfield, S. E.; Febres-Aldana, C. A.; Lee, J. J. K.; Chang, J. C.; Herzberg, B. O.; Selenica, P.; Woo, H. J.; Vanderbilt, C. M.; Yang, S. R.; more...
Cancer Discovery (2025)

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Automated real-world data integration improves cancer outcome prediction

Journal Article

Jee, J.; Fong, C.; Pichotta, K.; Tran, T. N.; Luthra, A.; Waters, M.; Fu, C.; Altoe, M.; Liu, S. Y.; Maron, S. B.; more...
Nature (2024)

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Lung neuroendocrine neoplasms harboring ALK, RET and other receptor tyrosine kinase fusions: Spectrum of pathologic features from conventional neuroendocrine carcinomas to unusual carcinoid-type tumors with focal mucin or adenocarcinoma components

Meeting Abstract

Armstrong, S.; Chang, J.; Yang, S. R.; Samuel, T.; Hussain, S.; Velez, M.; Baine, M.; Travis, W.; Drilon, A.; Quintanal-Villalonga, A.; more...
Laboratory Investigation (2024)

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Minimally-invasive molecular diagnosis of infiltrating brainstem gliomas through cerebrospinal fluid cell-free DNA sequencing

Meeting Abstract

Hill, K.; Giantini-Larsen, A.; Hickman, R. A.; Holle, B. M.; Ucpinar, B. A.; Alano, T.; Doe-Tetteh, S.; DiNapoli, S.; Riviere-Cazaux, C.; Burns, T. C.; more...
Neuro-Oncology (2024)

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A pan-cancer analysis of SMARCA4 alterations and the unique clinicogenomic characteristics associated with SMARCA4 mutation types

Meeting Abstract

Gormally, M.; Repetto, M.; Jee, J.; Chang, J. C.; Selenica, P.; Gazzo, A.; Richards, A. L.; Donoghue, M.; Aghajanian, C.; Reis-Filho, J. S.; more...
Journal of Clinical Oncology (2024)

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Optimal systemic treatment and real-world clinical application of ctDNA in patients with metastatic HER2-mutant lung cancer

Journal Article

Liu, S. Y.; Erazo, T.; Jee, J.; Arfe, A.; Gupta, A.; Pike, L. R. G.; Santini, F. C.; Daly, B.; Schoenfeld, A.; Eichholz, J.; more...
European Journal of Cancer (2024)

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Diffuse pleural mesotheliomas with genomic near-haploidization: A newly recognized subset with distinct clinical, histologic, and molecular features

Journal Article

Yang, S. R.; Jayakumaran, G.; Benhamida, J.; Febres-Aldana, C. A.; Fanaroff, R.; Chang, J.; Gedvilaite, E.; Villafania, L. B.; Sauter, J. L.; Offin, M.; more...
Clinical Cancer Research (2024)

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Microsatellite instability and mismatch repair deficiency define a distinct subset of lung cancers characterized by smoking exposure, high tumor mutational burden, and recurrent somatic MLH1 inactivation