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Chi-Chao Chen

  1. "GSK Faculty"
Formats
  1. Journal Article (13)
  2. Meeting Abstract (4)
  3. Research Letter (1)
Groups
  1. Center for Hematologic Malignancies (18)
  2. Executive Committee, Center for Hematologic Malignancies (18)
  3. GSK Faculty (18)
  4. MSK Grad Students (18)
  5. Sloan Kettering Institute Postdocs (18)
  6. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (17)

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People
  1. Scott Lowe (17)
  2. John Morris IV (7)
  3. Sha Tian (7)
  4. Yu-jui Ho (7)
  5. Chun-Hao Huang (6)
  6. Elisa De Stanchina (6)

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Years
  1. 2025 (1)
  2. 2023 (1)
  3. 2022 (2)
  4. 2020 (3)
  5. 2019 (2)
  6. 2018 (4)

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Publications
  1. Blood (3)
  2. Cancer Cell (3)
  3. Cancer Discovery (2)
  4. Cancer Research (2)
  5. Nature (2)
  6. Proceedings of the National Academy of Sciences of the United States of America (2)

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Publishers
  1. American Association for Cancer Research (4)
  2. American Society of Hematology (3)
  3. Cell Press (3)
  4. Nature Publishing Group (3)
  5. American Association for the Advancement of Science (2)
  6. National Academy of Sciences (2)

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Results (18)

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  • α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia
    Journal Article

    Millman, S. E.; Chaves-Perez, A.; Janaki-Raman, S.; Ho, Y. J.; Morris, J. P. 4th; Narendra, V.; Chen, C. C.; Jackson, B. T.; Yashinskie, J. J.; Mezzadra, R.; more...
    Blood (2025)

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  • MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer
    Journal Article

    Zhu, C.; Soto-Feliciano, Y. M.; Morris, J. P.; Huang, C. H.; Koche, R. P.; Ho, Y. J.; Banito, A.; Chen, C. W.; Shroff, A.; Tian, S.; more...
    eLife (2023)

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  • OGDH Is a genetic vulnerability and therapeutic target in acute myeloid leukemia
    Meeting Abstract

    Millman, S. E.; Chaves-Perez, A.; Morris, J. P. 4th; Chen, C. C.; Ho, Y. J.; Raman, S. J.; Yashinskie, J. J.; Mezzadra, R.; Narendra, V.; Tian, S.; more...
    Blood (2022)

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  • A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets
    Journal Article

    Li, X.; Huang, C. H.; Sánchez-Rivera, F. J.; Kennedy, M. C.; Tschaharganeh, D. F.; Morris, J. P. 4th; Montinaro, A.; O'Rourke, K. P.; Banito, A.; Wilkinson, J. E.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2022)

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  • CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity
    Meeting Abstract

    Zhang, Z.; Zhou, C.; Li, X.; Barnes, S.; Deng, S.; Hoover, E.; Chen, C. C.; Lee, Y. S.; Wang, C.; Tirado, C.; more...
    Cancer Research (2020)

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  • Loss of CHD1 promotes heterogeneous mechanisms of resistance to AR-targeted therapy via chromatin dysregulation
    Journal Article

    Zhang, Z.; Zhou, C.; Li, X.; Barnes, S. D.; Deng, S.; Hoover, E.; Chen, C. C.; Lee, Y. S.; Zhang, Y.; Wang, C.; more...
    Cancer Cell (2020)

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  • Vitamin B6 addiction in acute myeloid leukemia
    Journal Article

    Chen, C. C.; Li, B.; Millman, S. E.; Chen, C.; Li, X.; Morris, J. P. 4th; Mayle, A.; Ho, Y. J.; Loizou, E.; Liu, H.; more...
    Cancer Cell (2020)

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  • α-Ketoglutarate links p53 to cell fate during tumour suppression
    Research Letter

    Morris, J. P. 4th; Yashinskie, J. J.; Koche, R.; Chandwani, R.; Tian, S.; Chen, C. C.; Baslan, T.; Marinkovic, Z. S.; Sánchez-Rivera, F. J.; Leach, S. D.; more...
    Nature (2019)

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  • A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor FOXH1
    Journal Article

    Loizou, E.; Banito, A.; Livshits, G.; Ho, Y. J.; Koche, R. P.; Sánchez-Rivera, F. J.; Mayle, A.; Chen, C. C.; Kinalis, S.; Bagger, F. O.; more...
    Cancer Discovery (2019)

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  • Dependency of spliceosomal mutant MDS on innate immune signaling
    Meeting Abstract

    Lee, S. C.; North, K.; Chen, C. C.; Kim, E.; Lu, S. X.; Ki, M.; Garippa, R.; Lowe, S. W.; Bradley, R. K.; Abdel-Wahab, O. I.
    Blood (2018)

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