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Jaclyn Frances Hechtman

  1. "2017"
Formats
  1. Journal Article (16)
  2. Meeting Abstract (13)
  3. Book Section (1)
Groups
  1. Department of Pathology and Laboratory Medicine (26)
  2. Department of Medicine (19)
  3. Solid Tumor Oncology Division (19)
  4. GSK Faculty (18)
  5. Human Oncology and Pathogenesis Program (17)
  6. Center for Molecular Imaging and Biotechnology (CMIB) (12)

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People
  1. David Klimstra (13)
  2. Efsevia Vakiani (13)
  3. Jinru Shia (12)
  4. Ahmet Zehir (10)
  5. David Hyman (10)
  6. Marc Ladanyi (10)

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Years
  1. 2017 (30)
Publications
  1. Modern Pathology (5)
  2. Laboratory Investigation (4)
  3. Journal of Clinical Oncology (3)
  4. Clinical Cancer Research (2)
  5. American Journal of Surgical Pathology (1)
  6. Annals of Oncology (1)

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Publishers
  1. Nature Publishing Group (6)
  2. American Association for Cancer Research (5)
  3. Nature Research (5)
  4. American Society of Clinical Oncology (4)
  5. Elsevier Inc. (2)
  6. Oxford University Press (2)

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Results (30)

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  • Pan-TRK immunohistochemistry is an efficient and reliable screen for the detection of NTRK fusions
    Journal Article

    Hechtman, J. F.; Benayed, R.; Hyman, D. M.; Drilon, A.; Zehir, A.; Frosina, D.; Arcila, M. E.; Dogan, S.; Klimstra, D. S.; Ladanyi, M.; more...
    American Journal of Surgical Pathology (2017)

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  • Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: New recommendations, methods, and considerations
    Journal Article

    Hechtman, J. F.; Middha, S.; Stadler, Z. K.; Zehir, A.; Berger, M. F.; Vakiani, E.; Weiser, M. R.; Ladanyi, M.; Saltz, L. B.; Klimstra, D. S.; more...
    Familial Cancer (2017)

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  • Clinical features and outcomes of patients with colorectal cancers harboring NRAS mutations
    Journal Article

    Cercek, A.; Braghiroli, M. I.; Chou, J. F.; Hechtman, J. F.; Kemeny, N.; Saltz, L.; Capanu, M.; Yaeger, R.
    Clinical Cancer Research (2017)

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  • A next-generation TRK kinase inhibitor overcomes acquired resistance to prior TRK kinase inhibition in patients with TRK fusion-positive solid tumors
    Journal Article

    Drilon, A.; Nagasubramanian, R.; Blake, J. F.; Ku, N.; Tuch, B. B.; Ebata, K.; Smith, S.; Lauriault, V.; Kolakowski, G. R.; Brandhuber, B. J.; more...
    Cancer Discovery (2017)

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  • Subclinical focal cholangitis mimicking liver metastasis in asymptomatic patients with history of pancreatic ductal adenocarcinoma and biliary tree intervention
    Journal Article

    Horvat, N.; Godfrey, E. M.; Sadler, T. J.; Hechtman, J. F.; Tang, L. H.; Sigel, C. S.; Monti, S.; Mannelli, L.
    Cancer Imaging (2017)

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  • Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
    Journal Article

    Zehir, A.; Benayed, R.; Shah, R. H.; Syed, A.; Middha, S.; Kim, H. R.; Srinivasan, P.; Gao, J.; Chakravarty, D.; Devlin, S. M.; more...
    Nature Medicine (2017)

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  • Chromosome 20q amplification defines a subtype of microsatellite stable, left-sided colon cancers with wild-type RAS/RAF and better overall survival
    Journal Article

    Ptashkin, R. N.; Pagan, C.; Yaeger, R.; Middha, S.; Shia, J.; O'Rourke, K. P.; Berger, M. F.; Wang, L.; Cimera, R.; Wang, J.; more...
    Molecular Cancer Research (2017)

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  • Pan-TRK IHC is an efficient and reliable screening assay for targetable NTRK fusions
    Meeting Abstract

    Hechtman, J. F.; Drilon, A.; Hyman, D. M.; Zehir, A.; Dogan, S.; Arcila, M. E.; Ladanyi, M.; Benayed, R.; Jungbluth, A.
    Modern Pathology (2017)

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  • HER2/ ERBB2 amplification in colorectal carcinoma is associated with KRAS wild type status, microsatellite stability, and left sided tumors
    Meeting Abstract

    Cotzia, P.; Alex, D.; Middha, S.; Hechtman, J.; Liu, S.; Rao, D.; Vakiani, E.; Klimstra, D. S.; Shia, J.
    Modern Pathology (2017)

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  • Expression of PD-L1 in colorectal carcinoma (CRC) primarily occurs in stromal/immune cells at tumor-stroma interface (TSI), and is associated with high tumor-infiltrating lymphocytes (TILs) irrespective of the microsatellite instability (MSI) status or the molecular mechanism of MSI
    Meeting Abstract

    Liu, S.; Hechtman, J.; Segal, N.; Smith, J.; Rao, D.; Markowitz, A.; Weiser, M.; Vakiani, E.; Klimstra, D. S.; Stadler, Z.; more...
    Modern Pathology (2017)

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