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Jaclyn Frances Hechtman

  1. "Genitourinary Oncology Service"
Formats
  1. Journal Article (30)
  2. Meeting Abstract (25)
Groups
  1. Department of Medicine (55)
  2. GSK Faculty (55)
  3. Genitourinary Oncology Service (55)
  4. Solid Tumor Oncology Division (55)
  5. Human Oncology and Pathogenesis Program (53)
  6. Center for Molecular Imaging and Biotechnology (CMIB) (52)

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People
  1. David Solit (52)
  2. Michael Berger (40)
  3. Nikolaus Schultz (35)
  4. Yelena Janjigian (25)
  5. Geoffrey Ku (20)
  6. David Ilson (19)

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Years
  1. 2025 (1)
  2. 2023 (1)
  3. 2022 (1)
  4. 2021 (5)
  5. 2020 (5)
  6. 2019 (15)

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Publications
  1. Journal of Clinical Oncology (21)
  2. Clinical Cancer Research (8)
  3. Annals of Oncology (3)
  4. JCO Precision Oncology (3)
  5. Cancer Discovery (2)
  6. Cancer Research (2)

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Publishers
  1. American Society of Clinical Oncology (24)
  2. American Association for Cancer Research (13)
  3. Oxford University Press (5)
  4. Nature Publishing Group (3)
  5. American Medical Association (2)
  6. Springer (2)

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Results (55)

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  • Mechanisms of acquired resistance to BRAF V600E inhibition in colon cancers converge on RAF dimerization and are sensitive to its inhibition
    Journal Article

    Yaeger, R.; Yao, Z.; Hyman, D. M.; Hechtman, J. F.; Vakiani, E.; Zhao, H.; Su, W.; Wang, L.; Joelson, A.; Cercek, A.; more...
    Cancer Research (2017)

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  • Real-time genomic profiling of pancreatic ductal adenocarcinoma: Potential actionability and correlation with clinical phenotype
    Journal Article

    Lowery, M. A.; Jordan, E. J.; Basturk, O.; Ptashkin, R. N.; Zehir, A.; Berger, M. F.; Leach, T.; Herbst, B.; Askan, G.; Maynard, H.; more...
    Clinical Cancer Research (2017)

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  • Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
    Journal Article

    Zehir, A.; Benayed, R.; Shah, R. H.; Syed, A.; Middha, S.; Kim, H. R.; Srinivasan, P.; Gao, J.; Chakravarty, D.; Devlin, S. M.; more...
    Nature Medicine (2017)

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  • Genomic profiling of pancreas ductal adenocarcinoma (PDA), actionability, and correlation with clinical phenotype
    Meeting Abstract

    Jordan, E.; Lowery, M. A.; Ptashkin, R.; Zehir, A.; Berger, M. F.; Maynard, H.; Glassman, D. C.; Covington, C. M.; Schultz, N.; Abou-Alfa, G. K.; more...
    Journal of Clinical Oncology (2016)

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  • Emergence of RTK/RAS/PI3K pathway alterations in trastuzumab-refractory HER2-positive esophagogastric (EG) tumors
    Meeting Abstract

    Janjigian, Y. Y.; Sanchez-Vega, F.; Tuvy, Y.; Bouvier, N.; Riches, J. C.; Margolis, M.; Millang, B. M.; Scott, S. N.; Kundra, R.; Castel, P.; more...
    Journal of Clinical Oncology (2016)

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  • Somatic tumor profiling of DNA mismatch repair deficient (MMR-D) colorectal cancers (CRC)
    Meeting Abstract

    Ganesh, K.; Middha, S.; Hechtman, J. F.; Ashraf, A.; Tran, C.; Villano, D.; Yaeger, R. D.; Segal, N. H.; Cercek, A.; Varghese, A. M.; more...
    Journal of Clinical Oncology (2016)

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  • Clinical next generation sequencing (NGS) of esophagogastric (EG) adenocarcinomas identifies distinct molecular signatures of response to HER2 inhibition, first-line 5FU/platinum and PD1/CTLA4 blockade
    Meeting Abstract

    Janjigian, Y. Y.; Sanchez-Vega, F.; Jonsson, P.; Tuvy, Y.; Bouvier, N.; Riches, J.; Kundra, R.; Ku, G.; Hechtman, J. F.; Kelsen, D.; more...
    Annals of Oncology (2016)

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  • Genomic profiling and efficacy of anti-EGFR therapy in appendiceal adenocarcinoma
    Meeting Abstract

    Braghiroli, M.; Nash, G. M.; Morris, M.; Hechtman, J. F.; Vakiani, E.; Berger, M. F.; Solit, D. B.; Saltz, L.; Cercek, A.
    Journal of Clinical Oncology (2016)

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  • Reliable detection of mismatch repair deficiency in colorectal cancers using mutational load in next-generation sequencing panels
    Journal Article

    Stadler, Z. K.; Battaglin, F.; Middha, S.; Hechtman, J. F.; Tran, C.; Cercek, A.; Yaeger, R.; Segal, N. H.; Varghese, A. M.; Reidy-Lagunes, D. L.; more...
    Journal of Clinical Oncology (2016)

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  • Identification of targetable kinase alterations in patients with colorectal carcinoma that are preferentially associated with wild-type RAS/RAF
    Journal Article

    Hechtman, J. F.; Zehir, A.; Yaeger, R.; Wang, L.; Middha, S.; Zheng, T.; Hyman, D. M.; Solit, D.; Arcila, M. E.; Borsu, L.; more...
    Molecular Cancer Research (2016)

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