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Jaclyn Frances Hechtman

  1. "Gastrointestinal Oncology Service"
Formats
  1. Journal Article (58)
  2. Meeting Abstract (41)
  3. Guidelines (1)
  4. Research Letter (1)
Groups
  1. Department of Medicine (101)
  2. Gastrointestinal Oncology Service (101)
  3. Solid Tumor Oncology Division (101)
  4. Department of Pathology and Laboratory Medicine (82)
  5. GSK Faculty (82)
  6. Human Oncology and Pathogenesis Program (74)

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People
  1. Michael Berger (49)
  2. David Solit (47)
  3. Rona Yaeger (47)
  4. Jinru Shia (43)
  5. Nikolaus Schultz (41)
  6. Efsevia Vakiani (36)

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Years
  1. 2025 (1)
  2. 2024 (1)
  3. 2023 (2)
  4. 2022 (3)
  5. 2021 (10)
  6. 2020 (7)

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Publications
  1. Journal of Clinical Oncology (27)
  2. Modern Pathology (10)
  3. Clinical Cancer Research (9)
  4. JCO Precision Oncology (6)
  5. Annals of Oncology (5)
  6. Cancer Discovery (4)

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Publishers
  1. American Society of Clinical Oncology (33)
  2. American Association for Cancer Research (20)
  3. Nature Research (10)
  4. Nature Publishing Group (9)
  5. Oxford University Press (8)
  6. Springer (5)

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Results (101)

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  • Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic mutations
    Journal Article

    Wang, T.; Stadler, Z. K.; Zhang, L.; Weiser, M. R.; Basturk, O.; Hechtman, J. F.; Vakiani, E.; Saltz, L. B.; Klimstra, D. S.; Shia, J.
    Familial Cancer (2018)

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  • Genetic predictors of response to systemic therapy in esophagogastric cancer
    Journal Article

    Janjigian, Y. Y.; Sanchez-Vega, F.; Jonsson, P.; Chatila, W. K.; Hechtman, J. F.; Ku, G. Y.; Riches, J. C.; Tuvy, Y.; Kundra, R.; Bouvier, N.; more...
    Cancer Discovery (2018)

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  • Clinical sequencing defines the genomic landscape of metastatic colorectal cancer
    Journal Article

    Yaeger, R.; Chatila, W. K.; Lipsyc, M. D.; Hechtman, J. F.; Cercek, A.; Sanchez-Vega, F.; Jayakumaran, G.; Middha, S.; Zehir, A.; Donoghue, M. T. A.; more...
    Cancer Cell (2018)

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  • Correlation of benefit from immune checkpoint inhibitors with next gen sequencing (NGS) profiles in esophagogastric cancer (EGC) patients
    Meeting Abstract

    Ku, G. Y.; Sanchez-Vega, F.; Chatila, W.; Margolis, M.; Fein, C.; Ilson, D. H.; Hechtman, J. F.; Tuvy, Y.; Bouvier, N.; Kundra, R.; more...
    Journal of Clinical Oncology (2017)

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  • Mechanisms of acquired resistance to BRAF V600E inhibition in colon cancers converge on RAF dimerization and are sensitive to its inhibition
    Journal Article

    Yaeger, R.; Yao, Z.; Hyman, D. M.; Hechtman, J. F.; Vakiani, E.; Zhao, H.; Su, W.; Wang, L.; Joelson, A.; Cercek, A.; more...
    Cancer Research (2017)

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  • Real-time genomic profiling of pancreatic ductal adenocarcinoma: Potential actionability and correlation with clinical phenotype
    Journal Article

    Lowery, M. A.; Jordan, E. J.; Basturk, O.; Ptashkin, R. N.; Zehir, A.; Berger, M. F.; Leach, T.; Herbst, B.; Askan, G.; Maynard, H.; more...
    Clinical Cancer Research (2017)

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  • Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: New recommendations, methods, and considerations
    Journal Article

    Hechtman, J. F.; Middha, S.; Stadler, Z. K.; Zehir, A.; Berger, M. F.; Vakiani, E.; Weiser, M. R.; Ladanyi, M.; Saltz, L. B.; Klimstra, D. S.; more...
    Familial Cancer (2017)

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  • Clinical features and outcomes of patients with colorectal cancers harboring NRAS mutations
    Journal Article

    Cercek, A.; Braghiroli, M. I.; Chou, J. F.; Hechtman, J. F.; Kemeny, N.; Saltz, L.; Capanu, M.; Yaeger, R.
    Clinical Cancer Research (2017)

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  • Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
    Journal Article

    Zehir, A.; Benayed, R.; Shah, R. H.; Syed, A.; Middha, S.; Kim, H. R.; Srinivasan, P.; Gao, J.; Chakravarty, D.; Devlin, S. M.; more...
    Nature Medicine (2017)

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  • Chromosome 20q amplification defines a subtype of microsatellite stable, left-sided colon cancers with wild-type RAS/RAF and better overall survival
    Journal Article

    Ptashkin, R. N.; Pagan, C.; Yaeger, R.; Middha, S.; Shia, J.; O'Rourke, K. P.; Berger, M. F.; Wang, L.; Cimera, R.; Wang, J.; more...
    Molecular Cancer Research (2017)

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