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Jaclyn Frances Hechtman

  1. "Clinical Genetics Service"
Formats
  1. Meeting Abstract (25)
  2. Journal Article (24)
Groups
  1. Center for Pancreatic Cancer Research (49)
  2. Clinical Genetics Service (49)
  3. Department of Medicine (49)
  4. Population Sciences Research Program (49)
  5. Solid Tumor Oncology Division (49)
  6. Department of Pathology and Laboratory Medicine (48)

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People
  1. Zsofia Stadler (49)
  2. Jinru Shia (43)
  3. Efsevia Vakiani (28)
  4. Michael Berger (23)
  5. Martin Weiser (22)
  6. David Klimstra (21)

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Years
  1. 2025 (1)
  2. 2023 (1)
  3. 2021 (3)
  4. 2020 (5)
  5. 2019 (14)
  6. 2018 (10)

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Publications
  1. Journal of Clinical Oncology (11)
  2. Modern Pathology (11)
  3. Laboratory Investigation (5)
  4. Familial Cancer (3)
  5. Annals of Oncology (2)
  6. Cancer Research (2)

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Publishers
  1. American Society of Clinical Oncology (12)
  2. Nature Research (11)
  3. Nature Publishing Group (6)
  4. American Association for Cancer Research (4)
  5. Elsevier Inc. (3)
  6. Oxford University Press (3)

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Results (49)

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  • In colorectal carcinoma (CRC), true tumor cell staining for PD-L1 is uncommon and occurs in sporadic microsatellite-instable tumors with loss of MHC-I
    Meeting Abstract

    Liu, S.; Vyas, M.; Stadler, Z.; Weiser, M.; King, S.; Hechtman, J.; Vakiani, E.; Klimstra, D.; Shia, J.
    Modern Pathology (2018)

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  • Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic mutations
    Journal Article

    Wang, T.; Stadler, Z. K.; Zhang, L.; Weiser, M. R.; Basturk, O.; Hechtman, J. F.; Vakiani, E.; Saltz, L. B.; Klimstra, D. S.; Shia, J.
    Familial Cancer (2018)

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  • Genetic predictors of response to systemic therapy in esophagogastric cancer
    Journal Article

    Janjigian, Y. Y.; Sanchez-Vega, F.; Jonsson, P.; Chatila, W. K.; Hechtman, J. F.; Ku, G. Y.; Riches, J. C.; Tuvy, Y.; Kundra, R.; Bouvier, N.; more...
    Cancer Discovery (2018)

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  • Clinical sequencing defines the genomic landscape of metastatic colorectal cancer
    Journal Article

    Yaeger, R.; Chatila, W. K.; Lipsyc, M. D.; Hechtman, J. F.; Cercek, A.; Sanchez-Vega, F.; Jayakumaran, G.; Middha, S.; Zehir, A.; Donoghue, M. T. A.; more...
    Cancer Cell (2018)

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  • Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: New recommendations, methods, and considerations
    Journal Article

    Hechtman, J. F.; Middha, S.; Stadler, Z. K.; Zehir, A.; Berger, M. F.; Vakiani, E.; Weiser, M. R.; Ladanyi, M.; Saltz, L. B.; Klimstra, D. S.; more...
    Familial Cancer (2017)

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  • Expression of PD-L1 in colorectal carcinoma (CRC) primarily occurs in stromal/immune cells at tumor-stroma interface (TSI), and is associated with high tumor-infiltrating lymphocytes (TILs) irrespective of the microsatellite instability (MSI) status or the molecular mechanism of MSI
    Meeting Abstract

    Liu, S.; Hechtman, J.; Segal, N.; Smith, J.; Rao, D.; Markowitz, A.; Weiser, M.; Vakiani, E.; Klimstra, D. S.; Stadler, Z.; more...
    Modern Pathology (2017)

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  • Morphological characterization of colorectal cancers in the Cancer Genome Atlas reveals distinct morphology-molecular associations: Clinical and biological implications
    Journal Article

    Shia, J.; Schultz, N.; Kuk, D.; Vakiani, E.; Middha, S.; Segal, N. H.; Hechtman, J. F.; Berger, M. F.; Stadler, Z. K.; Weiser, M. R.; more...
    Modern Pathology (2017)

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  • Expression of PD-L1 in colorectal carcinoma (CRC) primarily occurs in stromal/immune cells at tumor-stroma interface (TSI), and is associated with high tumor-infiltrating lymphocytes (TILs) irrespective of the microsatellite instability (MSI) status or the molecular mechanism of MSI
    Meeting Abstract

    Liu, S.; Hechtman, J.; Segal, N.; Smith, J.; Rao, D.; Markowitz, A.; Weiser, M.; Vakiani, E.; Klimstra, D. S.; Stadler, Z.; more...
    Laboratory Investigation (2017)

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  • Clinical and genetic determinants of ovarian metastases from colorectal cancer
    Journal Article

    Ganesh, K.; Shah, R. H.; Vakiani, E.; Nash, G. M.; Skottowe, H. P.; Yaeger, R.; Cercek, A.; Lincoln, A.; Tran, C.; Segal, N. H.; more...
    Cancer (2017)

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  • Diagnosing colorectal medullary carcinoma: Interobserver variability and clinicopathological implications
    Journal Article

    Lee, L. H.; Yantiss, R. K.; Sadot, E.; Ren, B.; Calvacanti, M. S.; Hechtman, J. F.; Ivelja, S.; Huynh, B.; Xue, Y.; Shitilbans, T.; more...
    Human Pathology (2017)

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