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Richard Patrick Koche

Formats
  1. Journal Article (102)
  2. Meeting Abstract (75)
  3. Research Letter (2)
  4. Conference Paper (1)
Groups
  1. GSK Faculty (132)
  2. Sloan Kettering Institute Postdocs (117)
  3. Department of Medicine (106)
  4. Center for Hematologic Malignancies (97)
  5. Center for Molecular Imaging and Biotechnology (CMIB) (92)
  6. Hematologic Malignancies, Division of (71)

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People
  1. Ross Levine (42)
  2. Scott Armstrong (29)
  3. Elisa De Stanchina (28)
  4. Yingqian Zhan (28)
  5. Charles Rudin (19)
  6. Raajit Rampal (19)

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Years
  1. 2025 (9)
  2. 2024 (18)
  3. 2023 (18)
  4. 2022 (27)
  5. 2021 (25)
  6. 2020 (19)

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Publications
  1. Blood (46)
  2. Cancer Research (18)
  3. Cancer Discovery (15)
  4. Nature (7)
  5. Nature Communications (7)
  6. Cancer Cell (6)

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Publishers
  1. American Society of Hematology (48)
  2. American Association for Cancer Research (37)
  3. Nature Publishing Group (30)
  4. Cell Press (25)
  5. Elsevier Inc. (4)
  6. American Association for the Advancement of Science (3)

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Results (180)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Chromatin dynamics in vivo reveal a complex cell fate transition and master regulators of the development of pancreatic intraepithelial neoplasia
    Meeting Abstract

    Chandwani, R.; Osterhoudt, A.; Koche, R.; Leach, S. D.
    Cancer Research (2019)

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  • Cohesin members STAG1 and STAG2 display distinct roles in chromatin accessibility and topological control of HSC self-renewal and differentiation
    Journal Article

    Viny, A. D.; Bowman, R. L.; Liu, Y.; Lavallée, V. P.; Eisman, S. E.; Xiao, W.; Durham, B. H.; Navitski, A.; Park, J.; Braunstein, S.; more...
    Cell Stem Cell (2019)

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  • Therapeutic targeting of FLT3 mutations in AML via menin-MLL1 and FLT3 inhibition
    Meeting Abstract

    Dzama, M. M.; Taubert, M. C.; Kunz, K.; Rausch, J.; Chen, C. W.; Mupo, A.; Theobald, M.; Kindler, T.; Koche, R. P.; Vassiliou, G. S.; more...
    Cancer Research (2019)

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  • α-Ketoglutarate links p53 to cell fate during tumour suppression
    Research Letter

    Morris, J. P. 4th; Yashinskie, J. J.; Koche, R.; Chandwani, R.; Tian, S.; Chen, C. C.; Baslan, T.; Marinkovic, Z. S.; Sánchez-Rivera, F. J.; Leach, S. D.; more...
    Nature (2019)

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  • 2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation
    Journal Article

    Schvartzman, J. M.; Reuter, V. P.; Koche, R. P.; Thompson, C. B.
    Proceedings of the National Academy of Sciences of the United States of America (2019)

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  • A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid leukemia through the pluripotency factor FOXH1
    Journal Article

    Loizou, E.; Banito, A.; Livshits, G.; Ho, Y. J.; Koche, R. P.; Sánchez-Rivera, F. J.; Mayle, A.; Chen, C. C.; Kinalis, S.; Bagger, F. O.; more...
    Cancer Discovery (2019)

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  • Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation
    Journal Article

    Li, Q. V.; Dixon, G.; Verma, N.; Rosen, B. P.; Gordillo, M.; Luo, R.; Xu, C.; Wang, Q.; Soh, C. L.; Yang, D.; more...
    Nature Genetics (2019)

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  • PI3K inhibition activates SGK1 via a feedback loop to promote chromatin-based regulation of ER-dependent gene expression
    Journal Article

    Toska, E.; Castel, P.; Chhangawala, S.; Arruabarrena-Aristorena, A.; Chan, C.; Hristidis, V. C.; Cocco, E.; Sallaku, M.; Xu, G.; Park, J.; more...
    Cell Reports (2019)

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  • FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST)
    Meeting Abstract

    Ran, L.; Chen, Y.; Wong, W. P. E.; Li, D.; Cao, Z.; Shukla, S.; Xie, Y.; Zheng, D.; Koche, R. P.; Antonescu, C. R.; more...
    Cancer Research (2018)

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  • Functional profiling of patient AML stem cells reveals mechanisms of epigenetic plasticity controlling therapy resistance
    Meeting Abstract

    Takao, S.; Koche, R.; Cifani, P.; Ser, Z.; Kentsis, A.
    Blood (2018)

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