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Charles Rudin

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Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation

Journal Article

Elkrief, A.; Waters, N. R.; Smith, N.; Dai, A.; Slingerland, J.; Aleynick, N.; Febles, B.; Gogia, P.; Socci, N. D.; Lumish, M.; more...
Cancer Immunology Research (2024)

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Immune heterogeneity in small-cell lung cancer and vulnerability to immune checkpoint blockade

Journal Article

Nabet, B. Y.; Hamidi, H.; Lee, M. C.; Banchereau, R.; Morris, S.; Adler, L.; Gayevskiy, V.; Elhossiny, A. M.; Srivastava, M. K.; Patil, N. S.; more...
Cancer Cell (2024)

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Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer (Consolidative Use of Radiotherapy to Block [CURB] oligoprogression): An open-label, randomised, controlled, phase 2 study

Journal Article

Tsai, C. J.; Yang, J. T.; Shaverdian, N.; Patel, J.; Shepherd, A. F.; Eng, J.; Guttmann, D.; Yeh, R.; Gelblum, D. Y.; Namakydoust, A.; more...
Lancet (2024)

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Microsatellite instability and mismatch repair deficiency define a distinct subset of lung cancers characterized by smoking exposure, high tumor mutational burden, and recurrent somatic MLH1 inactivation

Journal Article

Yang, S. R.; Gedvilaite, E.; Ptashkin, R.; Chang, J.; Ziegler, J.; Mata, D. A.; Villafania, L. B.; Nafa, K.; Hechtman, J. F.; Benayed, R.; more...
Journal of Thoracic Oncology (2024)

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Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

Journal Article

Li, Z.; Zhuang, X.; Pan, C. H.; Yan, Y.; Thummalapalli, R.; Hallin, J.; Torborg, S.; Singhal, A.; Chang, J. C.; Manchado, E.; more...
Cancer Discovery (2024)

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SKYSCRAPER-02: Tiragolumab in combination with atezolizumab plus chemotherapy in untreated extensive-stage small-cell lung cancer

Journal Article

Rudin, C. M.; Liu, S. V.; Soo, R. A.; Lu, S.; Hong, M. H.; Lee, J. S.; Bryl, M.; Dumoulin, D. W.; Rittmeyer, A.; Chiu, C. H.; more...
Journal of Clinical Oncology (2024)

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Prognostic implications of small cell lung cancer (SCLC) transcriptional subtyping for central nervous system (CNS) metastases

Meeting Abstract

Skakodub, A.; Tringale, K.; Egger, J.; Eichholz, J.; Yu, Y.; Gomez, D.; Rimner, A.; Li, B.; Yamada, Y.; Wilcox, J.; more...
Neuro-Oncology (2023)

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Phase I dose escalation trial combining olaparib and thoracic radiation therapy in extensive-stage small cell lung cancer

Meeting Abstract

Rimner, A.; Lok, B.; Gelblum, D. Y.; Kotecha, R. R.; Albrecht, F.; Shin, J. Y.; Laplant, Q.; Namakydoust, A.; Shepherd, A.; Gomez, D.; more...
Journal of Thoracic Oncology (2023)

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CDC7 inhibition constrains lineage plasticity and prevents resistance and neuroendocrine transformation in the lung and prostate

Meeting Abstract

Quintanal-Villalonga, Á.; Zaidi, S.; Karthaus, W. R.; Zhan, Y. A.; Shafer, M.; Qiu, J.; de Stanchina, E.; Haffner, M. C.; Sawyers, C. L.; Rudin, C. M.
Annals of Oncology (2023)

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Outcomes of combination platinum-doublet chemotherapy and anti-PD(L)-1 blockade in KRAS(G12C) mutant non-small cell lung cancer

Journal Article

Elkrief, A.; Riccuiti, B.; Alessi, J. V.; Fei, T.; Kalvin, H. L.; Egger, J. V.; Rizvi, H.; Thummalapalli, R.; Lamberti, G.; Plodkowski, A.; more...
The Oncologist (2023)

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