Synapse - Charles Rudin

Results (202)

Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation

Journal Article

Elkrief, A.; Waters, N. R.; Smith, N.; Dai, A.; Slingerland, J.; Aleynick, N.; Febles, B.; Gogia, P.; Socci, N. D.; Lumish, M.; more...
Cancer Immunology Research (2024)

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Microsatellite instability and mismatch repair deficiency define a distinct subset of lung cancers characterized by smoking exposure, high tumor mutational burden, and recurrent somatic MLH1 inactivation

Journal Article

Yang, S. R.; Gedvilaite, E.; Ptashkin, R.; Chang, J.; Ziegler, J.; Mata, D. A.; Villafania, L. B.; Nafa, K.; Hechtman, J. F.; Benayed, R.; more...
Journal of Thoracic Oncology (2024)

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Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

Journal Article

Li, Z.; Zhuang, X.; Pan, C. H.; Yan, Y.; Thummalapalli, R.; Hallin, J.; Torborg, S.; Singhal, A.; Chang, J. C.; Manchado, E.; more...
Cancer Discovery (2024)

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CDC7 inhibition constrains lineage plasticity and prevents resistance and neuroendocrine transformation in the lung and prostate

Meeting Abstract

Quintanal-Villalonga, Á.; Zaidi, S.; Karthaus, W. R.; Zhan, Y. A.; Shafer, M.; Qiu, J.; de Stanchina, E.; Haffner, M. C.; Sawyers, C. L.; Rudin, C. M.
Annals of Oncology (2023)

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Outcomes of combination platinum-doublet chemotherapy and anti-PD(L)-1 blockade in KRAS(G12C) mutant non-small cell lung cancer

Journal Article

Elkrief, A.; Riccuiti, B.; Alessi, J. V.; Fei, T.; Kalvin, H. L.; Egger, J. V.; Rizvi, H.; Thummalapalli, R.; Lamberti, G.; Plodkowski, A.; more...
The Oncologist (2023)

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Clinical and molecular features of long-term response to immune checkpoint inhibitors in patients with advanced non–small cell lung cancer

Journal Article

Thummalapalli, R.; Ricciuti, B.; Bandlamudi, C.; Muldoon, D.; Rizvi, H.; Elkrief, A.; Luo, J.; Alessi, J. V.; Pecci, F.; Lamberti, G.; more...
Clinical Cancer Research (2023)

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Radiotheranostics targeting Delta-like ligand 3 expressing small-cell lung cancers

Meeting Abstract

Tendler, S.; Hoang, T.; Bauer, D.; Korsen, J.; Carter, L.; Michel, A.; Degregorio, R.; Pillarsetty, N.; Poirier, J. T.; Lewis, J. S.; more...
Journal of Thoracic Oncology (2023)

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Microsatellite instability defines a subset of lung cancers with smoking exposure, high tumor mutational burden and MLH1 inactivation

Meeting Abstract

Yang, S. R.; Gedvilaite, E.; Ptashkin, R.; Chang, J.; Ziegler, J.; Mata, D.; Villafania, L. B.; Nafa, K.; Hechtman, J. F.; Benhamida, J.; more...
Journal of Thoracic Oncology (2023)

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Identifying early and late hallmarks of plasticity in neuroendocrine transformation of lung cancer at single-cell level

Meeting Abstract

Chan, J. M.; Quintanal-Villalonga, A.; Sabet, A.; Manoj, P.; Masilionis, I.; Falcon, C.; Sohail, N.; Chun, J.; Nawy, T.; Mazutis, L.; more...
Journal of Thoracic Oncology (2023)

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Exportin 1 inhibition constraints lineage plasticity and histological transformation through downregulation of SOX2

Meeting Abstract

Quintanal-Villalonga, A.; Durani, V.; Sabet, A.; Redin, E.; Kawasaki, K.; Shaffer, M.; Manoj, P.; Sridhar, H.; Haffner, M. C.; Sawyers, C. L.; more...
Journal of Thoracic Oncology (2023)

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