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Andrew Michael Intlekofer

  1. "Cancer Biology and Genetics Program Faculty"
Formats
  1. Journal Article (9)
  2. Meeting Abstract (5)
Groups
  1. Cancer Biology and Genetics Program Faculty (14)
  2. Center for Hematologic Malignancies (14)
  3. Center for Molecular Imaging and Biotechnology (CMIB) (14)
  4. Department of Medicine (14)
  5. GSK Faculty (14)
  6. Hematologic Malignancies Research (14)

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People
  1. Craig Thompson (14)
  2. Ross Levine (6)
  3. Alan Shih (5)
  4. Justin Cross (5)
  5. Arien Rustenburg (4)
  6. John Chodera (4)

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Years
  1. 2018 (3)
  2. 2017 (5)
  3. 2015 (2)
  4. 2014 (2)
  5. 2013 (2)
Publications
  1. Blood (4)
  2. Cancer Discovery (2)
  3. Cell Metabolism (2)
  4. Cancer Research (1)
  5. Genes and Development (1)
  6. Journal of Clinical Investigation (1)

More Publications

Publishers
  1. American Society of Hematology (4)
  2. American Association for Cancer Research (3)
  3. Elsevier Inc. (2)
  4. Nature Publishing Group (2)
  5. American Society for Clinical Investigation (1)
  6. Cold Spring Harbor Laboratory Press (1)

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Results (14)

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  • As extracellular glutamine levels decline, asparagine becomes an essential amino acid
    Journal Article

    Pavlova, N. N.; Hui, S.; Ghergurovich, J. M.; Fan, J.; Intlekofer, A. M.; White, R. M.; Rabinowitz, J. D.; Thompson, C. B.; Zhang, J.
    Cell Metabolism (2018)

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  • Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations
    Journal Article

    Intlekofer, A. M.; Shih, A. H.; Wang, B.; Nazir, A.; Rustenburg, A. S.; Albanese, S. K.; Patel, M.; Famulare, C.; Correa, F. M.; Takemoto, N.; more...
    Nature (2018)

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  • JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition
    Journal Article

    McKenney, A. S.; Lau, A. N.; Hanasoge Somasundara, A. V.; Spitzer, B.; Intlekofer, A. M.; Ahn, J.; Shank, K.; Rapaport, F. T.; Patel, M. A.; Papalexi, E.; more...
    Journal of Clinical Investigation (2018)

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  • Spliceosomal dysfunction Is a critical mediator of IDH2 mutant leukemogenesis
    Meeting Abstract

    Yoshimi, A.; Lin, K. T.; Wiseman, D.; Intlekofer, A. M.; Wang, B.; Pastore, A.; Rahman, M.; Lee, S. C. W.; Liu, B.; Micol, J. B.; more...
    Blood (2017)

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  • Generation and application of T-cell lymphoma patient derived tumor xenograft models
    Meeting Abstract

    Fiore, D.; Wang, X.; Khodos, I.; Di Giacomo, F.; Gaudiano, M.; Phillip, J. M.; Wang, R.; Yang, Z.; Ginsberg, M.; Intlekofer, A. M.; more...
    Blood (2017)

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  • Epigenetic identity in AML depends on disruption of nonpromoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers
    Journal Article

    Glass, J. L.; Hassane, D.; Wouters, B. J.; Kunimoto, H.; Avellino, R.; Garrett-Bakelman, F. E.; Guryanova, O. A.; Bowman, R.; Redlich, S.; Intlekofer, A. M.; more...
    Cancer Discovery (2017)

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  • Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia
    Journal Article

    Shih, A. H.; Meydan, C.; Shank, K.; Garrett-Bakelman, F. E.; Ward, P. S.; Intlekofer, A. M.; Nazir, A.; Stein, E. M.; Knapp, K.; Glass, J.; more...
    Cancer Discovery (2017)

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  • L-2-hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
    Journal Article

    Intlekofer, A. M.; Wang, B.; Liu, H.; Shah, H.; Carmona-Fontaine, C.; Rustenburg, A. S.; Salah, S.; Gunner, M. R.; Chodera, J. D.; Cross, J. R.; more...
    Nature Chemical Biology (2017)

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  • Stereochemistry matters: L-2HG as a tumor response to hypoxia
    Meeting Abstract

    Thompson, C. B.; Intlekofer, A. M.; DeMatteo, R. G.; Venneti, S.; Finley, L. W. S.; Lu, C.; Rustenburg, A. S.; Grinaway, P. B.; Chodera, J. D.; Cross, J. R.; more...
    Cancer Research (2015)

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  • Hypoxia induces production of L-2-hydroxyglutarate
    Journal Article

    Intlekofer, A. M.; DeMatteo, R. G.; Venneti, S.; Finley, L. W. S.; Lu, C.; Judkins, A. R.; Rustenburg, A. S.; Grinaway, P. B.; Chodera, J. D.; Cross, J. R.; more...
    Cell Metabolism (2015)

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