Research Focus

Former Employee. Pediatrics; NE Agency Contingent

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1. Leukemia-reactive cytotoxic CD8(+) and CD4(+) T-cells specific for novel WT-1 epitopes are generated in vitro by sensitization with overlapping pentadecapeptides (15-mers) spanning the wilms tumor protein

   Meeting Abstract

   Doubrovina, E.; Dupont, J.; Kanaeva, E.; O'Reilly, R. J.
   Blood (2007)

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2. In vivo eradication of human clonigenic acute lyrnphoblastic leukemic cells expressing the Wilms tumor protein, WT-1, by HLA restricted WT-1 specific T-cells in NOD/SCID mice monitored by bioluminescent imaging

   Meeting Abstract

   Doubrovina, E.; Doubrovin, M.; Kanaeva, E.; O'Reilly, R. J.
   Blood (2007)

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3. Differences in the phenotype and in vivo anti-tumor activity of wti specific and ebv-specific T-cells generated in vitro for adoptive immunotherapy

   Meeting Abstract

   Doubrovina, E.; Dupont, J.; Kanaeva, E.; Doubrovin, M.; O'reilly, R.
   Biology of Blood and Marrow Transplantation (2006)

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