Synapse - Zhan Yao

Results (38)

Diverse kinase mutations and fusions drive non-Langerhans cell histiocytoses

Meeting Abstract

Durham, B.; Diamond, E.; Yao, Z.; Ma, J.; Choi, J.; Kim, E.; Lee, S.; Gao, Y.; Micol, J. B.; Campbell, P.; more...
Pediatric Blood and Cancer (2015)

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Oncogenic RAF mutants that signal as functional dimers are resistant to current RAF inhibitors but sensitive to a novel inhibitor of RAF dimer kinase activity

Meeting Abstract

Yao, Z.; Torres, N. M.; Wei, M.; Hanrahan, A.; Abdel-Wahab, O.; Solit, D.; Luo, L.; Poulikakos, P.; Rosen, N.
Molecular Cancer Research (2014)

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Oncogenic RAF mutants that signal as functional dimers are resistant to current RAF inhibitors but sensitive to a novel inhibitor of RAF dimer kinase activity

Meeting Abstract

Yao, Z.; Torres, M.; Wei, M.; Hanrahan, A.; Abdel-Wahab, O.; Solit, D.; Luo, L. S.; Poulikakos, P.; Rosen, N.
Cancer Research (2014)

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Acquired resistance to rapamycin and mTOR kinase inhibitors is mediated by non-overlapping mutations in distinct sites in the mTOR protein

Meeting Abstract

Rodrik - Outmezguine, V. S.; Yao, Z.; Mukherjee, R.; Cai, L.; Barratt, D.; Ward, R.; Klinowska, T.; Destanchina, E.; Berger, M.; Baselga, J.; more...
Cancer Research (2014)

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Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence

Journal Article

Nissan, M. H.; Pratilas, C. A.; Jones, A. M.; Ramirez, R.; Won, H.; Liu, C.; Tiwari, S.; Kong, L.; Hanrahan, A. J.; Yao, Z.; more...
Cancer Research (2014)

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Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS-ERK signaling

Journal Article

Will, M.; Qin, A. C. R.; Toy, W.; Yao, Z.; Rodrik-Outmezguine, V. ; Schneider, C.; Huang, X.; Monian, P.; Jiang, X.; de Stanchina, E.; more...
Cancer Discovery (2014)

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Acquired resistance to rapamycin and mTOR kinase inhibitors is mediated by non-overlapping mutations in distinct sites in the mTOR protein

Meeting Abstract

Rodrik-Outmezguine, V.; Yao, Z.; Berger, M.; De Stanchina, E.; Klinowska, T.; Barratt, D.; Baselga, J.; Rosen, N.
Cancer Research (2013)

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Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS signaling

Meeting Abstract

Will, M.; Toy, W.; Yao, Z.; Poulikakos, P.; Rodrik-Outmezguine, V. ; Schneider, C.; Paul, J.; Baselga, J.; Liu, N.; Rosen, N.; more...
Cancer Research (2013)

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