Synapse - Sarcoma Service

Results (953)

Efficacy, safety, and patient-reported outcomes of vimseltinib in patients with tenosynovial giant cell tumor: Results from the phase 3 MOTION trial

Meeting Abstract

Tap, W. D.; Bhadri, V.; Stacchiotti, S.; Bauer, S.; Wagner, A. J.; de Sande, M. V.; Bernthal, N. M.; Pousa, A. L.; Razak, A. R. A.; Italiano, A.; more...
Journal of Clinical Oncology (2024)

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Lete-cel in patients with synovial sarcoma or myxoid/round cell liposarcoma: Planned interim analysis of the pivotal IGNYTE-ESO trial

Meeting Abstract

D'Angelo, S. P.; Furness, A. J. S.; Thistlethwaite, F.; Burgess, M. A.; Riedel, R. F.; Haanen, J.; Noujaim, J.; Chalmers, A. W.; Pousa, Alpo; Chugh, R.; more...
Journal of Clinical Oncology (2024)

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Phase 1 study of NB003, a broad-spectrum KIT/PDGFRα inhibitor, in patients with advanced gastrointestinal stromal tumors (GIST)

Meeting Abstract

Li, J.; Chi, P.; Kang, Y. K.; Cao, H.; George, S.; Zhang, J.; Zhang, J.; Hu, K.; Zhang, L. J.; Xu, Y. H.
Journal of Clinical Oncology (2024)

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Proteomic analysis in patients with dedifferentiated liposarcoma (DDLPS) in a phase Ia/Ib study of the MDM2-p53 antagonist brigimadlin

Meeting Abstract

Jaimes, Y.; LoRusso, P.; Sturm, G.; Gounder, M. M.; Yamamoto, N.; Somaiah, N.; Lugowska, I. A.; Moreno, V.; Peltzer, A.; Teufel, M.; more...
Journal of Clinical Oncology (2024)

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Peak part 1 summary: A phase 3, randomized, open-label multicenter clinical study of bezuclastinib (CGT9486) and sunitinib combination versus sunitinib in patients with gastrointestinal stromal tumors (GIST)

Meeting Abstract

Wagner, A. J.; Trent, J. C.; Attia, S.; Agulnik, M.; Wilky, B. A.; Tap, W. D.; von Mehren, M.; Davis, E. J.; Zou, L.; Shah, N.; more...
Journal of Clinical Oncology (2024)

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Treatment of patients with dedifferentiated liposarcoma (DDLPS) with the MDM2-p53 antagonist brigimadlin and p53 function: A longitudinal analysis of circulating microRNAs (miRNAs) in a first-in-human phase Ia/Ib study

Meeting Abstract

Peltzer, A.; LoRusso, P.; Gounder, M. M.; Yamamoto, N.; Somaiah, N.; Lugowska, I. A.; Moreno, V.; Teufel, M.; Jayadeva, G.; Hesse, R.; more...
Journal of Clinical Oncology (2024)

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DCC-3116 in combination with ripretinib for patients with advanced gastrointestinal stromal tumor: A phase 1/2 study

Meeting Abstract

Chandana, S. R.; Shepard, D. R.; Mehnert, J. M.; Chi, P.; Trent, J. C.; Psoinos, C. M.; Zhou, B.; Black, V.; Viswanathan, L.; Gozo, M.; more...
Journal of Clinical Oncology (2024)

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Alliance A091902: A multicenter randomized phase II trial of paclitaxel (P) with or without nivolumab (N) in patients (pts) with advanced angiosarcoma (AS)

Meeting Abstract

Grilley-Olson, J. E.; Allred, J. B.; Schuetze, S.; Davis, E. J.; Poklepovic, A. S.; Wagner, M. J.; Riedel, R. F.; Hartranft, A.; Welliver, M. X.; Berg, S. A.; more...
Journal of Clinical Oncology (2024)

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Preliminary results from FLAGSHP-1: A phase 1 study of ERAS-601 as a monotherapy or in combination with cetuximab in patients (pts) previously treated for advanced chordoma

Meeting Abstract

Gounder, M. M.; Rosen, E.; Parikh, A. R.; Conley, A. P.; Hong, D. S.; Sheth, S.; Mai, N.; Sgroe, E.; Mitchell, R.; Picard, R.; more...
Journal of Clinical Oncology (2024)

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Phase 1 results of the WEE1 inhibitor, azenosertib, in combination with gemcitabine (gem) in adult and pediatric patients (pts) with relapsed or refractory (R/R) osteosarcoma

Meeting Abstract

Avutu, V.; Livingston, J. A.; Federman, N.; Cranmer, L. D.; Gaspar, N.; Toulmonde, M.; Pressey, J. G.; Brahmi, M.; Poklepovic, A. S.; Shi, Q.; more...
Journal of Clinical Oncology (2024)

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