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A phase I trial of AVA6000, a fibroblast activation protein (FAP)-released, tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumors

Meeting Abstract

Twelves, C. J.; Banerji, U.; Tap, W. D.; Cook, N.; Evans, T. R. J.; Plummer, R.; Anthoney, A.; Plummer, C.; Dawson, R.; Loadman, P.; more...
Annals of Oncology (2024)

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Updated efficacy and safety of vimseltinib in patients (pts) with tenosynovial giant cell tumor (TGCT): One-year follow-up from the MOTION phase III trial

Meeting Abstract

Gelderblom, H.; Bhadri, V. A.; Stacchiotti, S.; Bauer, S.; Wagner, A. J.; van de Sande, M.; Bernthal, N. M.; Lopez Pousa, A.; Abdul Razak, A. R.; Italiano, A.; more...
Annals of Oncology (2024)

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Response to treatment with nab-Sirolimus in patients with perivascular epithelioid cell sarcoma of gynecologic or peritoneal origin: Subgroup analysis from AMPECT

Meeting Abstract

Herzog, T.; Dockery, L.; Dickson, M.; Ganjoo, K.; Ravi, V.; Ding, L.; Schmid, A.; Palma, N.; Navarro, W.; Wagner, A.
Gynecologic Oncology (2024)

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Targeted CRISPR-Knockout (KO) screening to identify FOXF1 regulators and therapeutic strategies in gastrointestinal stromal tumor (GIST)

Meeting Abstract

Tomas, F.; Cho, W. H.; Li, D.; Callychurn, V. R.; Wang, N.; Yu, C.; Chi, P.
European Journal of Cancer (2024)

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Histology-specific clinical trial of lenvatinib and pembrolizumab in patients with sarcoma

Journal Article

Movva, S.; Seier, K.; Avutu, V.; Banks, L. B.; Chan, J.; Chi, P.; Dickson, M. A.; Gounder, M. M.; Kelly, C. M.; Keohan, M. L.; more...
Clinical Cancer Research (2024)

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A single-arm phase 2 trial of trametinib in patients with locally advanced or metastatic epithelioid hemangioendothelioma

Journal Article

Schuetze, S. M.; Ballman, K. V.; Heise, R.; Ganjoo, K. N.; Davis, E. J.; George, S.; Burgess, M. A.; Choy, E.; Shepard, D. R.; Tinoco, G.; more...
Clinical Cancer Research (2024)

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Safety and efficacy of pembrolizumab, radiation therapy, and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity (SU2C-SARC032): An open-label, randomised clinical trial

Journal Article

Mowery, Y. M.; Ballman, K. V.; Hong, A. M.; Schuetze, S. M.; Wagner, A. J.; Monga, V.; Heise, R. S.; Attia, S.; Choy, E.; Burgess, M. A.; more...
Lancet (2024)

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GDF-15 predicts epithelioid hemangioendothelioma aggressiveness and is downregulated by sirolimus through ATF4/ATF5 suppression

Journal Article

Stacchiotti, S.; Martini, S.; Pasquali, S.; Frezza, A. M.; Beretta, A.; Percio, S.; Lecchi, M.; Tortoreto, M.; Barisella, M.; Collini, P.; more...
Clinical Cancer Research (2024)

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MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor

Journal Article

Miranda-Román, M. A.; Lee, C. J.; Fishinevich, E.; Ran, L.; Patel, A. J.; Yan, J.; Khudoynazarova, M. N.; Warda, S.; Pachai, M. R.; Chen, Y.; more...
Clinical Cancer Research (2024)

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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

Journal Article

Lee, J. H.; Sánchez-Rivera, F. J.; He, L.; Basnet, H.; Chen, F. X.; Spina, E.; Li, L.; Torner, C.; Chan, J. E.; Yarlagadda, D. V. K.; more...
Cell (2024)

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