Synapse - Sarcoma Service

Results (953)

Identification of response stratification factors from pooled efficacy analyses of afamitresgene autoleucel ("Afami-cel" [Formerly ADP-A2M4]) in metastatic synovial sarcoma and myxoid/round cell liposarcoma phase 1 and phase 2 trials

Meeting Abstract

D'Angelo, S. P.; Attia, S.; Blay, J. Y.; Strauss, S. J.; Morales, C. M. V.; Razak, A. R. A.; Van Winkle, E.; Annareddy, T.; Sattigari, C.; Diamantopoulos, E.; more...
Journal of Clinical Oncology (2022)

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A phase 1b lead-in to a randomized phase 2 trial of lurbinectedin plus doxorubicin in leiomyosarcoma (LMS)

Meeting Abstract

Cote, G. M.; Choy, E.; Thornton, K. A.; Mazzola, E.; Bouberhan, S.; Merriam, P.; Wagner, A. J.; Morgan, J. A.; Haddox, C. L.; Oza, J.; more...
Journal of Clinical Oncology (2022)

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Results of a phase I dose escalation and expansion study of tegavivint (BC2059), a first-in-class TBL1 inhibitor for patients with progressive, unresectable desmoid tumor

Meeting Abstract

Cranmer, L. D.; Razak, A. R. A.; Ratan, R.; Choy, E.; George, S.; Liebner, D. A.; Stenehjem, D. D.; Gounder, M. M.
Journal of Clinical Oncology (2022)

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Primary efficacy and safety of letetresgene autoleucel (lete-cel; GSK3377794) pilot study in patients with advanced and metastatic myxoid/round cell liposarcoma (MRCLS)

Meeting Abstract

D'Angelo, S. P.; Druta, M.; Van Tine, B. A.; Liebner, D. A.; Schuetze, S.; Nathenson, M.; Holmes, A. P.; D'Souza, J.; Kapoor, G. S.; Zajic, S.; more...
Journal of Clinical Oncology (2022)

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TTI-621-03: A phase I/II study of TTI-621 in combination with doxorubicin in patients with unresectable or metastatic high-grade leiomyosarcoma (LMS)

Meeting Abstract

Chawla, S. P.; Kelly, C. M.; Gordon, E. M.; Quon, D. V.; Moradkhani, A.; Chua-Alcala, V. S.; Thompson, T. M.; Scheuber, A.; Bruns, I.; Allgood, V. E.; more...
Journal of Clinical Oncology (2022)

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A phase 1/2 dose-escalation and dose-expansion study of ZN-c3 in combination with gemcitabine in adult and pediatric subjects with relapsed or refractory osteosarcoma

Meeting Abstract

Avutu, V.; Slotkin, E. K.; Livingston, J. A. A.; Chawla, S. P.; Pressey, J. G.; Nandkumar, P.; Zheng, C.; Misir, S.; Pultar, P.; Voliotis, D.; more...
Journal of Clinical Oncology (2022)

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ZENYTH-ESO: Master protocol to assess the safety and recommended phase II dose of next generation NY-ESO-1-specific TCR T-cells in HLA-A*02 patients with synovial sarcoma and myxoid/round cell liposarcoma [Substudy 3, GSK4427296]

Meeting Abstract

Araujo, D. M.; Ladle, B. H.; He, K.; Powers, B.; McGillivray, A.; Mitrica, I.; Liu, W.; Patel, N.; D'Angelo, S. P.
Journal of Clinical Oncology (2022)

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Growth factor signaling and kinase inhibitors regulate oncogenesis in desmoid fibromatosis by modulating activity of the beta-catenin transcription target ABL1

Meeting Abstract

Hu, J.; Villano, A.; O'Connor, R.; Rozenberg, Y.; Venkatesh, A.; Gounder, M.; Socci, N.; Singer, S.; Hameed, M.; Crago, A. M.
Clinical Cancer Research (2022)

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Enrollment of pediatric and adolescent patients with MAGE-A4+advanced synovial sarcoma into cohort 2 of SPEARHEAD-1: A phase 2 trial of afamitresgene autoleucel ("afami-cel" [formerly ADP-A2M4])

Meeting Abstract

Lunt, C.; D'Angelo, S. P.; Razak, A. R. A.; Wagner, M. J.; Van Tine, B. A.; Ganjoo, K.; Blay, J. Y.; Araujo, D. M.; Agulnik, M.; Glod, J. W.; more...
Clinical Cancer Research (2022)

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Myxoid pleomorphic liposarcoma is distinguished from other liposarcomas by widespread loss of heterozygosity and significantly worse overall survival: A genomic and clinicopathologic study

Journal Article

Dermawan, J. K.; Hwang, S.; Wexler, L.; Tap, W. D.; Singer, S.; Vanderbilt, C. M.; Antonescu, C. R.
Modern Pathology (2022)

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