Synapse - Sarcoma Service

Results (953)

An interpretable AI model for recurrence prediction after surgery in gastrointestinal stromal tumour: An observational cohort study

Journal Article

Bertsimas, D.; Margonis, G. A.; Tang, S.; Koulouras, A.; Antonescu, C. R.; Brennan, M. F.; Martin-Broto, J.; Rutkowski, P.; Stasinos, G.; Wang, J.; more...
eClinicalMedicine (2023)

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Results of an open-label, phase Ia/b study of pembrolizumab plus olaratumab in patients with unresectable, locally advanced, or metastatic soft-tissue sarcoma

Journal Article

Sch€offski, P.; Bahleda, R.; Wagner, A. J.; Burgess, M. A.; Junker, N.; Chisamore, M.; Peterson, P.; Szpurka, A. M.; Ceccarelli, M.; Tap, W. D.
Clinical Cancer Research (2023)

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SARC041: A phase 3 randomized double-blind study of abemaciclib versus placebo in patients with advanced dedifferentiated liposarcoma

Meeting Abstract

Dickson, M. A.; Ballman, K. V.; Weiss, M. C.; Attia, S.; Wagner, M. J.; Pollack, S.; Choy, E.; Wagner, A. J.; Wilky, B. A.; Davis, L. E.; more...
Journal of Clinical Oncology (2023)

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Phase 1 dose-expansion study of oral TP-1287, a cyclin-dependent kinase 9 (CDK9) inhibitor, in patients with Ewing sarcoma (EWS)

Meeting Abstract

Cote, G. M.; Wagner, A. J.; Charlson, J. A.; Hu, J. S.; Dickson, M. A.; D'Amato, G. Z.; Kabir, S.; Xu, B.; Lebedinsky, C.; von Mehren, M.
Journal of Clinical Oncology (2023)

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A phase II study of palbociclib combined with retifanlimab in patients with advanced dedifferentiated liposarcoma

Meeting Abstract

D'Angelo, S. P.; Rosenbaum, E.; Gularte Mérida, R.; Dickson, M. A.; Keohan, M. L.; Gounder, M. M.; Chi, P.; Movva, S.; Kelly, C. M.; Avutu, V.; more...
Journal of Clinical Oncology (2023)

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NOTOS: A pivotal study of navtemadlin, a first-in-class mouse double minute 2 inhibitor (MDM2i), in patients (pts) with TP53 wild-type (TP53(WT)) Merkel cell carcinoma (MCC) for whom anti PD-1/L1 therapy has failed

Meeting Abstract

Wong, M. K. K.; Burgess, M. A.; Chandra, S.; Fecher, L. A.; Gaudy-Marqueste, C.; Silk, A. W.; Hanna, G. J.; Lebbe, C.; Quéreux, G.; Rabinowits, G.; more...
Journal of Clinical Oncology (2023)

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INSIGHT: A phase 3, randomized, multicenter, open-label study of ripretinib vs sunitinib in patients with advanced gastrointestinal stromal tumor previously treated with imatinib harboring KIT exon 11 + 17 and/or 18 mutations

Meeting Abstract

George, S.; Blay, J. Y.; Chi, P.; Jones, R. L.; Serrano, C.; Somaiah, N.; Reichmann, W.; Sprott, K.; Achour, H.; Sherman, M. L.; more...
Journal of Clinical Oncology (2023)

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ENVASARC: A pivotal trial of envafolimab and envafolimab in combination with ipilimumab in patients with advanced or metastatic undifferentiated pleomorphic sarcoma or myxofibrosarcoma who have progressed on prior chemotherapy

Meeting Abstract

Riedel, R. F.; Chawla, S. P.; Druta, M.; Jones, R. L.s; Schuetze, S.; Lam, J.; Zhuang, D.; Freddo, J. L.; Adams, B. J.; Theuer, C. P.; more...
Journal of Clinical Oncology (2023)

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A phase 2, open-label, adaptive, dose-ranging study with long-term extension to evaluate the safety, tolerability, efficacy, and pharmacokinetics of intra-articular AMB-05X injections in patients with tenosynovial giant cell tumor

Meeting Abstract

Gelderblom, H.; Bhadri, V.; Randall, R. L.; Scharschmidt, T.; Tap, W. D.; Alani, L.; Johnson, K.; Leyva, S.; Nguyen, D. D.; Nguyen, T.; more...
Journal of Clinical Oncology (2023)

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Survivorship in patients with cardiac metastases defined by cardiac magnetic resonance imaging in relation to lesion hypoperfusion

Meeting Abstract

Jain, R.; Liberman, N.; Agoglia, H.; Park, M.; Park, R.; Jessurun, J.; Tap, W. D.; Kim, J.; Steingart, R.; Liu, J.; more...
Journal of Clinical Oncology (2023)

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