Synapse - Genitourinary Oncology Service

Results (17)

Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors

Journal Article

Hyman, D. M.; Snyder, A. E.; Carvajal, R. D.; Gerecitano, J. F.; Voss, M. H.; Ho, A. L.; Konner, J.; Winkelmann, J. L.; Stasi, M. A.; Monson, K. R.; more...
Cancer Chemotherapy and Pharmacology (2015)

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Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma

Journal Article

Motzer, R. J.; Hutson, T. E.; Hudes, G. R.; Figlin, R. A.; Martini, J. F.; English, P. A.; Huang, X.; Valota, O.; Williams, J. A.
Cancer Chemotherapy and Pharmacology (2014)

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A phase 1b clinical trial of the multi-targeted tyrosine kinase inhibitor lenvatinib (E7080) in combination with everolimus for treatment of metastatic renal cell carcinoma (RCC)

Journal Article

Molina, A. M.; Hutson, T. E.; Larkin, J.; Gold, A. M.; Wood, K.; Carter, D.; Motzer, R.; Michaelson, M. D.
Cancer Chemotherapy and Pharmacology (2014)

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Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma

Journal Article

Harmon, C. S.; Deprimo, S. E.; Figlin, R. A.; Hudes, G. R.; Hutson, T. E.; Michaelson, M. D.; Négrier, S.; Kim, S. T.; Huang, X.; Williams, J. A.; more...
Cancer Chemotherapy and Pharmacology (2014)

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A phase 2 study of intravenous panobinostat in patients with castration-resistant prostate cancer

Journal Article

Rathkopf, D. E.; Picus, J.; Hussain, A.; Ellard, S.; Chi, K. N.; Nydam, T.; Allen-Freda, E.; Mishra, K. K.; Porro, M. G.; Scher, H. I.; more...
Cancer Chemotherapy and Pharmacology (2013)

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Population pharmacokinetic analysis of 17-dimethylaminoethylamino-17- demethoxygeldanamycin (17-DMAG) in adult patients with solid tumors

Journal Article

Aregbe, A. O.; Sherer, E. A.; Egorin, M. J.; Scher, H. I.; Solit, D. B.; Ramanathan, R. K.; Ramalingam, S.; Belani, C. P.; Ivy, P. S.; Bies, R. R.
Cancer Chemotherapy and Pharmacology (2012)

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A phase I trial of docetaxel and pulse-dose 17-allylamino-17- demethoxygeldanamycin in adult patients with solid tumors

Journal Article

Iyer, G.; Morris, M. J.; Rathkopf, D.; Slovin, S. F.; Steers, M.; Larson, S. M.; Schwartz, L. H.; Curley, T.; Delacruz, A.; Ye, Q.; more...
Cancer Chemotherapy and Pharmacology (2012)

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Phase I rapid dose-escalation study of AGS-1C4D4, a human anti-PSCA (prostate stem cell antigen) monoclonal antibody, in patients with castration-resistant prostate cancer: A PCCTC trial

Journal Article

Antonarakis, E. S.; Carducci, M. A.; Eisenberger, M. A.; Denmeade, S. R.; Slovin, S. F.; Jelaca-Maxwell, K.; Vincent, M. E.; Scher, H. I.; Morris, M. J.
Cancer Chemotherapy and Pharmacology (2012)

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A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer

Journal Article

Rathkopf, D.; Wong, B. Y.; Ross, R. W.; Anand, A.; Tanaka, E.; Woo, M. M.; Hu, J.; Dzik-Jurasz, A.; Yang, W.; Scher, H. I.
Cancer Chemotherapy and Pharmacology (2010)

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Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: Results of a pharmacokinetic/pharmacodynamic meta-analysis

Journal Article

Houk, B. E.; Bello, C. L.; Poland, B.; Rosen, L. S.; Demetri, G. D.; Motzer, R. J.
Cancer Chemotherapy and Pharmacology (2010)

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