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Early Drug Development Service

Formats
  1. Meeting Abstract (234)
  2. Journal Article (209)
  3. Review (7)
  4. Editorial (5)
  5. Research Letter (3)
  6. Miscellaneous (2)
  7. Book Section (1)
Groups
  1. Department of Medicine (461)
  2. Solid Tumor Oncology Division (461)
  3. GSK Faculty (244)
  4. Department of Pathology and Laboratory Medicine (200)
  5. Human Oncology and Pathogenesis Program (193)
  6. Gynecologic Medicine Service (186)

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People
  1. David Hyman (354)
  2. Alison Schram (123)
  3. Alexander Drilon (111)
  4. Michael Berger (111)
  5. David Solit (110)
  6. Marc Ladanyi (91)

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Years
  1. 2025 (6)
  2. 2024 (29)
  3. 2023 (18)
  4. 2022 (27)
  5. 2021 (27)
  6. 2020 (49)

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Publications
  1. Journal of Clinical Oncology (111)
  2. Annals of Oncology (38)
  3. Cancer Research (37)
  4. Clinical Cancer Research (33)
  5. Cancer Discovery (23)
  6. Blood (21)

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Publishers
  1. American Society of Clinical Oncology (126)
  2. American Association for Cancer Research (101)
  3. Oxford University Press (45)
  4. Elsevier Inc. (34)
  5. Nature Publishing Group (29)
  6. American Society of Hematology (23)

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Results (461)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Early phase I study of the PARP inhibitor veliparib (ART-888) alone or in combination with carboplatia/paclitaxel (CP) in patients with varying degrees of hepatic or renal dysfunction: A study of the NCI-Organ Dysfunction Working Group (ODG)
    Meeting Abstract

    Tawbi, H. A. H.; Chu, E.; Lin, Y.; Hyman, D. M.; Goel, S.; Rudek, M. A.; Dowlati, A.; LoRusso, P.; Mulkerin, D.; Chew, H. K.; more...
    Journal of Clinical Oncology (2014)

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  • VE-BASKET, a Simon 2-stage adaptive design, phase II, histology-independent study in nonmelanoma solid tumors harboring BRAF V600 mutations (V600m): Activity of vemurafenib (VEM) with or without cetuximab (CTX) in. colorectal cancer (CRC)
    Meeting Abstract

    Tabernero, J.; Chan, E.; Baselga, J.; Blay, J. Y.; Chau, I.; Hyman, D. M.; Raje, N. S.; Wolf, J.; Sirzén, F.; Veronese, M. L.; more...
    Journal of Clinical Oncology (2014)

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  • A phase 1 study of MEDI3617, a selective angiopoietin-2 inhibitor, alone and in combination with carboplatin/paclitaxel, paclitaxel, or bevacizmab in patients with advanced solid tumors
    Meeting Abstract

    Hyman, D. M.; Rizvi, N. A.; Natale, R. B.; Armstrong, D. K.; Birrer, M. J.; Recht, L. D.; Dotan, E.; Gribbin, M. J.; McDevitt, J. T.; Tavakkoli, F.; more...
    Journal of Clinical Oncology (2014)

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  • VE-BASKET, a first-in-kind, phase II, histology-independent "basket" study of vemurafenib (VEM) in nonmelanoma solid tumors harboring BRAF V600 mutations (V600m)
    Meeting Abstract

    Hyman, D. M.; Blay, J. Y.; Chau, I.; Raje, N. S.; Fernandez, M. E. E.; Wolf, J.; Sirzén, F.; Veronese, M. L.; Mitchell, L.; Puzanov, I.; more...
    Journal of Clinical Oncology (2014)

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  • Detection of BRAF mutations in urine and plasma cell-free DNA: Application to the diagnosis and management of histiocytic disorder patients
    Meeting Abstract

    Abdel-Wahab, O. I.; Diamond, E. L.; Patel, M.; Holley, V. R.; Cabrilo, G.; Rampal, R.; Hassaine, L.; Kosco, K.; Baselga, J.; Kurzrock, R.; more...
    Journal of Clinical Oncology (2014)

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  • Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders
    Meeting Abstract

    Hyman, D. M.; Diamond, E.; Vibat, C. R.; Hassaine, L.; Poole, J.; Patel, M.; Holley, V.; Cabrilo, G.; Lu, T. T.; Arcila, M.; more...
    Blood (2014)

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  • The efficacy of vemurafenib in Erdheim-Chester disease and Langerhans cell histiocytosis: Preliminary results from VE-basket study
    Meeting Abstract

    Hyman, D. M.; Diamond, E.; Subbiah, V.; Blay, J. Y.; Lockhart, A. C.; Abdel-Wahab, O.; Sirzén, F.; Veronese, M. L.; Laserre, S. F.; Elez, E.; more...
    Blood (2014)

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  • Unraveling the molecular basis of Langerhans and non-Langerhans cell histiocytic neoplasms through whole exome sequencing
    Meeting Abstract

    Durham, B.; Ma, J.; Kim, E.; Choi, J. K.; Campbell, P.; Estrada-Veras, J.; Walsh, M. P.; Lacouture, M. E.; Chung, Y. R.; Nakitandwe, J.; more...
    Blood (2014)

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  • Visualization of orbital involvement of Erdheim-Chester disease on PET/CT
    Journal Article

    Beylergil, V.; Carrasquillo, J. A.; Hyman, D. M.; Diamond, E. L.
    Clinical Nuclear Medicine (2014)

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  • The performance of BRCA1 immunohistochemistry for detecting germline, somatic, and epigenetic BRCA1 loss in high-grade serous ovarian cancer
    Journal Article

    Meisel, J. L.; Hyman, D. M.; Garg, K.; Zhou, Q.; Dao, F.; Bisogna, M.; Gao, J.; Schultz, N. D.; Grisham, R. N.; Phillips, M.; more...
    Annals of Oncology (2014)

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