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Early Drug Development Service

Formats
  1. Meeting Abstract (235)
  2. Journal Article (209)
  3. Review (7)
  4. Editorial (5)
  5. Research Letter (3)
  6. Miscellaneous (2)
  7. Book Section (1)
Groups
  1. Department of Medicine (462)
  2. Solid Tumor Oncology Division (462)
  3. GSK Faculty (244)
  4. Department of Pathology and Laboratory Medicine (200)
  5. Human Oncology and Pathogenesis Program (193)
  6. Gynecologic Medicine Service (187)

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People
  1. David Hyman (354)
  2. Alison Schram (124)
  3. Alexander Drilon (111)
  4. Michael Berger (111)
  5. David Solit (110)
  6. Marc Ladanyi (91)

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Years
  1. 2025 (7)
  2. 2024 (29)
  3. 2023 (18)
  4. 2022 (27)
  5. 2021 (27)
  6. 2020 (49)

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Publications
  1. Journal of Clinical Oncology (112)
  2. Annals of Oncology (38)
  3. Cancer Research (37)
  4. Clinical Cancer Research (33)
  5. Cancer Discovery (23)
  6. Blood (21)

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Publishers
  1. American Society of Clinical Oncology (127)
  2. American Association for Cancer Research (101)
  3. Oxford University Press (45)
  4. Elsevier Inc. (34)
  5. Nature Publishing Group (29)
  6. American Society of Hematology (23)

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Results (462)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Masterkey-01: Phase I/II, open-label multicenter study to assess safety, tolerability, pharmacokinetics, and antitumor activity of BDTX-189, an inhibitor of allosteric ErbB mutations, in patients with advanced solid malignancies
    Meeting Abstract

    Hamilton, E. P.; Patel, M. R.; Rodon, J.; Hong, D. S.; Schram, A. M.; Janne, P. A.; LoRusso, P.; Sachdev, J. C.; Ou, S. H.; Buck, E. A.; more...
    Journal of Clinical Oncology (2020)

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  • Basket study of the oral progesterone antagonist onapristone ER in women with progesterone receptor positive (PR plus ) recurrent granulosa cell tumor (GCT), low-grade serous ovarian cancer (LGSOC), or endometrioid endometrial cancer (EEC)
    Meeting Abstract

    Grisham, R. N.; Li, K.; Iasonos, A.; Girshman, J.; Cadoo, K. A.; Kyi, C.; Makker, V.; Cohen, S. M.; O'Cearbhaill, R. E.; Sabbatini, P.; more...
    Journal of Clinical Oncology (2020)

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  • The utility of plasma ctDNA for detection of KRAS G12C and other mutations in lung cancers
    Meeting Abstract

    Murciano-Goroff, Y. R.; Arbour, K. C.; Offin, M. D.; Tu, H. Y. Y.; Lebow, E. S.; Shaffer, T. S.; Bertucci, C.; Hosseini, S. A.; Garg, K.; Lim, L. P.; more...
    Cancer Research (2020)

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  • Kinase fusions drive endocrine resistance in estrogen receptor-positive breast cancer
    Meeting Abstract

    Liu, B.; Ross, D. S.; Schram, A. M.; Razavi, P.; Lagana, S. M.; Zhang, Y.; Scaltriti, M.; Bromberg, J. F.; Ladanyi, M.; Hyman, D. M.; more...
    Cancer Research (2020)

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  • TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
    Meeting Abstract

    Cocco, E.; Lee, J. E.; Kannan, S.; Schram, A. M.; Won, H. H.; Shifman, S.; Kulick, A.; Baldino, L.; Toska, E.; Arena, S.; more...
    Cancer Research (2020)

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  • Oncologic therapy shapes the fitness landscape of clonal hematopoiesis
    Meeting Abstract

    Bolton, K. L.; Ptashkin, R. N.; Gao, T.; Braunstein, L.; Devlin, S. M.; Patel, M.; Berthon, A.; Syed, A.; Yabe, M.; Coombs, C.; more...
    Cancer Research (2020)

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  • Immune and genomic profiling of small cell carcinomas of the ovary hypercalcemic type
    Meeting Abstract

    Dessources, K.; Holland, A.; Liu, J. D.; Lee, S. S.; Selenica, P.; Wu, M.; Stylianou, A.; Reis-Filho, J.; Hyman, D. M.; Hollmann, T. J.; more...
    Gynecologic Oncology (2020)

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  • Community partnerships expand access to tumor molecular profiling
    Meeting Abstract

    Reynolds, T.; Jack, K.; Kemeny, M.; Bulone, L.; Gonsky, J.; Kampel, L. J.; Hyman, D.; Solit, D. B.; Conklin, C.; McMillan, S.; more...
    Cancer Epidemiology Biomarkers and Prevention (2020)

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  • Cancer therapy shapes the fitness landscape of clonal hematopoiesis
    Journal Article

    Bolton, K. L.; Ptashkin, R. N.; Gao, T.; Braunstein, L.; Devlin, S. M.; Kelly, D.; Patel, M.; Berthon, A.; Syed, A.; Yabe, M.; more...
    Nature Genetics (2020)

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  • Larotrectinib versus prior therapies in tropomyosin receptor kinase fusion cancer: An intra-patient comparative analysis
    Journal Article

    Italiano, A.; Nanda, S.; Briggs, A.; Garcia-Foncillas, J.; Lassen, U.; Vassal, G.; Kummar, S.; van Tilburg, C. M.; Hong, D. S.; Laetsch, T. W.; more...
    Cancers (2020)

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