Synapse - Solid Tumor Oncology Division

Results (22161)

Dual-vector-transduction with single-step magnetic selection (Zip-sort) increases transgenic payloads to enhance CAR T cell activity

Meeting Abstract

James, S. E.; Chen, S.; Ng, B.; Fischman, J.; Jahn, L.; Boardman, A. P.; Rajagopalan, A.; Elias, H. K.; Massa, A. R.; Manuele, D.; more...
Blood (2024)

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TroFuse-015: A phase III study of trophoblast antigen 2 (TROP2)—directed antibody-drug conjugate sacituzumab tirumotecan (sac-TMT) vs treatment of physician's choice (TPC) for previously treated metastatic gastroesophageal adenocarcinoma (GEA)

Meeting Abstract

Shitara, K.; Wainberg, Z. A.; van Cutsem, E.; Janjigian, Y. Y.; Xu, R. H.; Oh, D. Y.; Xu, J.; Wu, S.; Bhaumik, S.; Bhagia, P.; more...
Annals of Oncology (2024)

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A phase Ib/II open-label study evaluating trastuzumab deruxtecan (T-DXd) in combination with rilvegostomig and chemotherapy in patients with HER2-positive (HER2+) and HER2-low gastric or gastroesophageal junction adenocarcinoma (GEJA): DESTINY-Gastric03 Part 4

Meeting Abstract

Janjigian, Y. Y.; Lloyd, C.; de Giorgio-Miller, V. G.; Chang, Y. T.; Lee, J.
Annals of Oncology (2024)

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280P Efficacy of avelumab + axitinib (A + Ax) vs sunitinib (S) by number of IMDC risk factors in patients (pts) with advanced renal cell carcinoma (aRCC): Subgroup analyses from the final analysis of the phase III JAVELIN renal 101 trial

Meeting Abstract

Eto, M.; Motzer, R. J.; Choueiri, T. K.; Haanen, J. B. A. G.; Oya, M.; Uemura, H.; Venugopal, B.; Rini, B. I.; Miyake, H.; Albiges, L.; more...
Annals of Oncology (2024)

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292P Avelumab + axitinib (A + Ax) vs sunitinib (S) in patients (pts) with advanced renal cell carcinoma (aRCC): Subgroup analyses by age from the final analysis of the phase III JAVELIN Renal 101 trial

Meeting Abstract

Oya, M.; Motzer, R. J.; Choueiri, T. K.; Haanen, J. B. A. G.; Eto, M.; Uemura, H.; Venugopal, B.; Rini, B. I.; Miyake, H.; Albiges, L.; more...
Annals of Oncology (2024)

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Five-year overall survival (OS) and OS by baseline liver function from the phase III HIMALAYA study of tremelimumab (T) plus durvalumab (D) in unresectable hepatocellular carcinoma (uHCC)

Meeting Abstract

Kudo, M.; Rimassa, L.; Chan, S. L.; Sangro, B.; Lau, G.; Breder, V. V.; Varela, M.; Crysler, O. V.; Bouattour, M.; Dao, V. T.; more...
Annals of Oncology (2024)

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Final overall survival for the phase III, KEYNOTE-811 study of pembrolizumab plus trastuzumab and chemotherapy for HER2+advanced, unresectable or metastatic G/GEJ adenocarcinoma

Meeting Abstract

Rha, S. Y.; Kawazoe, A.; Bai, Y.; Xu, J.; Lonardi, S.; Metges, J. P.; Weber, P. E. Y.; Wyrwicz, L. S.; Shen, L.; Ostapenko, Y. V.; more...
Annals of Oncology (2024)

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EDGE-Gastric Arm A1: Phase II study of domvanalimab (D), zimberelimab (Z), and FOLFOX in first-line (1L) advanced gastroesophageal (GE) cancer

Meeting Abstract

Rha, S. Y.; Oh, D. Y.; Pelster, M.; Wainberg, Z. A.; Sison, A.; Scott, J.; Nelson, S.; Wishengrad, D.; Rhee, J.; Nuyten, D. S. A.; more...
Annals of Oncology (2024)

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Genetic drivers and cellular selection of female mosaic X chromosome loss

Journal Article

Liu, A.; Genovese, G.; Zhao, Y.; Pirinen, M.; Zekavat, S. M.; Kentistou, K. A.; Yang, Z.; Yu, K.; Vlasschaert, C.; Liu, X.; more...
Nature (2024)

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Benchmarking Embedding Aggregation Methods in Computational Pathology: A Clinical Data Perspective

Conference Paper

Chen, S.; Campanella, G.; Elmas, A.; Stock, A.; Zeng, J.; Polydorides, A. D.; Schoenfeld, A. J.; Huang, K. L.; Houldsworth, J.; Vanderbilt, C.; more...
Journal Machine Learning Research (2024)

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