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Results (13287)

Oncogenic RAF mutants that signal as functional dimers are resistant to current RAF inhibitors but sensitive to a novel inhibitor of RAF dimer kinase activity

Meeting Abstract

Yao, Z.; Torres, M.; Wei, M.; Hanrahan, A.; Abdel-Wahab, O.; Solit, D.; Luo, L. S.; Poulikakos, P.; Rosen, N.
Cancer Research (2014)

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Investigations into the tumor specific regulation of HER2 by Grp94 in breast cancer

Meeting Abstract

Yan, P.; Patel, H.; Yang, C.; Taldone, T.; Chiosis, G.
Cancer Research (2014)

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Human cone precursor-derived retinoblastoma tumors

Meeting Abstract

Xu, X. L.; Singh, H. P.; Wang, L.; Qi, D. L.; Poulos, B. K.; Abramson, D. H.; Jhanwar, S. C.; Cobrinik, D.
Cancer Research (2014)

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Enhanced adipogenesis of bone marrow-derived stromal cells by ovarian cancer cells via BMP4 and IL8 is associated with increase in cancer stem/progenitor cells and cancer cell proliferation

Meeting Abstract

Wong, E. W. P.; Shen, L. B.; Shieh, J.H.; Moore, M. A. S.
Cancer Research (2014)

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Glioma-associated IDH mutation induces miR-34a repression and stem cell-like physiology through enhanced PDGF signaling

Meeting Abstract

Silber, J.; Harinath, G.; Parthasarathy, P. T.; Fabius, A. W. M.; Turcan, S.; Chan, T. A.; Huse, J. T.
Cancer Research (2014)

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The antitumor effects of PI3K beta inhibitors in PTEN negative prostate cancer are enhanced by inhibition of reactivated PI3K alpha signaling

Meeting Abstract

Schwartz, S.; Carver, B. S.; Wongvipat, J.; Rodrik-Outmezguine, V. ; Destanchina, E.; Trigwell, C.; Barry, S.; Baselga, J.; Chandarlapaty, S.; Scher, H. I.; more...
Cancer Research (2014)

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Blockade of EGFR and HER3 enhances PI3K/Akt antitumor activity in triple negative breast cancer

Meeting Abstract

Scaltriti, M.; Tao, J.; Castel, P.; Radosevic-Robin, N.; Elkabets, M.; Auricchio, N.; Juric, D.; Penault-Llorca, F.; Baselga, J.
Cancer Research (2014)

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PNA as novel targeted cancer therapy for BRAF(V600E) mutant melanoma

Meeting Abstract

Rothman, J. H.; Surriga, O.; Vasudeva, S. D.; Ambrosini, G.; Ouerfelli, O.; Schwartz, G. K.
Cancer Research (2014)

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Acquired resistance to rapamycin and mTOR kinase inhibitors is mediated by non-overlapping mutations in distinct sites in the mTOR protein

Meeting Abstract

Rodrik - Outmezguine, V. S.; Yao, Z.; Mukherjee, R.; Cai, L.; Barratt, D.; Ward, R.; Klinowska, T.; Destanchina, E.; Berger, M.; Baselga, J.; more...
Cancer Research (2014)

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Dual lineage inhibition of ETV1 and KIT disrupts the ETV1-KIT feed forward circuit and potentiates imatinib antitumor effect in GIST oncogenesis

Meeting Abstract

Ran, L.; Sirota, I.; Cao, Z.; Murphy, D.; Shukla, S.; Rossi, F.; Wongvipat, J.; Tap, W. D.; Besmer, P.; Antonescu, C. R.; more...
Cancer Research (2014)

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