Synapse - Human Oncology and Pathogenesis Program

Results (5987)

OTT-MAL activates the Notch signaling transcription factor RBPJ and cooperates with mutant MPL to induce acute megakaryoblastic leukemia

Meeting Abstract

Mercher, T.; Raffel, G. D.; Moore, S. A.; Cornejo, M. G.; Baudry-Bluteau, D.; Cagnard, N.; Jesneck, J.; Pikman, Y.; Cullen, D. E.; Williams, I.; more...
Blood (2008)

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NFIB: A gene consistently upregulated in MPD and frequently co-amplified with JAK2V617F augments growth of erythropoietin dependent cells

Meeting Abstract

Lin, X. Q.; Buzzai, M.; Levine, R. L.; Berkofsky-Fessler, W.; Zhang, W. J.; Ebert, B. L.; Gilliland, D. G.; Licht, J. D.
Blood (2008)

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Dasatinib is associated with durable treatment responses in chronic phase chronic myeloid leukemia: Long-term follow-up from the phase I trial (Ca180002)

Meeting Abstract

Cortes, J.; Sawyers, C. L.; Kantarjian, H. M.; Shah, N. P.; Paquette, R.; Bleickardt, E.; Paliwal, P.; Talpaz, M.
Haematologica (2008)

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Comprehensive survey of kinase pathway mutations in poorly differentiated thyroid carcinomas using high-throughput mass spectrometry-based genotyping

Meeting Abstract

Chitale, D. A.; Ryder, M.; Filho, J. C. R.; Knauff, J.; Ladanyi, M.; Fagin, J.; Ghossein, R.
Modern Pathology (2008)

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A comprehensive survey of kinase pathway mutations in poorly differentiated thyroid carcinomas using high-throughput mass spectrometry-based genotyping

Meeting Abstract

Chitale, D. A.; Ryder, M.; Filho, J. C. R.; Knauff, J.; Ladanyi, M.; Fagin, J.; Ghossein, R.
Laboratory Investigation (2008)

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An integrated analysis of gene expression, copy number alterations, and kinase pathway mutations in lung adenocarcinoma reveals frequent loss of the MAPK phosphatase Gene DUSP4 in EGFR mutant tumors

Meeting Abstract

Chitale, D.; Gong, Y.; Broderick, S.; Brennan, C.; Taylor, B. S.; Somwar, R.; Wang, L.; Motoi, N.; Szoke, J.; Sander, C.; more...
Laboratory Investigation (2008)

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An integrated analysis of gene expression, copy number alterations, and kinase pathway mutations in lung adenocarcinoma reveals frequent loss of the MAPK phosphatase gene DUSP4 in EGFR mutant tumors

Meeting Abstract

Chitale, D.; Gong, Y.; Broderick, S.; Brennan, C.; Taylor, B. S.; Somwar, R.; Wang, L.; Motoi, N.; Szoke, J.; Sander, C.; more...
Modern Pathology (2008)

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Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

Journal Article

Zakrzewski, J. L.; Suh, D.; Markley, J. C.; Smith, O. M.; King, C.; Goldberg, G. L.; Jenq, R.; Holland, A. M.; Grubin, J.; Cabrera-Perez, J.; more...
Nature Biotechnology (2008)

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Heterogeneity of breast cancer metastases: Comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases

Journal Article

Wu, J. M.; Fackler, M. J.; Halushka, M. K.; Molavi, D. W.; Taylor, M. E.; Wei, W. T.; Griffin, C.; Fetting, J.; Davidson, N. E.; De Marzo, A. M.; more...
Clinical Cancer Research (2008)

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Functional copy-number alterations in cancer

Journal Article

Taylor, B. S.; Barretina, J.; Socci, N. D.; Decarolis, P.; Ladanyi, M.; Meyerson, M.; Singer, S.; Sander, C.
PLoS ONE (2008)

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