Synapse - Department of Medicine

Results (39634)

Colorectal cancer: Fecal occult blood testing, flexible sigmoidoscopy, colonoscopy, and potential role of genetic markers

Meeting Abstract

Markowitz, A. J.
Clinical Chemistry (1999)

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The Hsp90 chaperone system as a potential therapeutic target: Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases

Meeting Abstract

Zheng, F. Z. F.; Münster, P. N.; Kuduk, S.; Danishefsky, S.; Sepp-Lorenzino, L.; Rosen, N.
Clinical Cancer Research (1999)

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The use of the prostate xenograft CWR22 and its androgen independent sublines in the preclinical development of herceptin

Meeting Abstract

Higgins, B.; Fox, W. D.; Maiese, K.; Fazzari, M.; Scher, H. I.; Agus, D. B.
Clinical Cancer Research (1999)

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Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by co-administration of ZD1839 (Iressa™), an inhibitor of EGF receptor tyrosine kinase

Meeting Abstract

Sirotnak, F. M.; Miller, V. A.; Scher, H. I.; Kris, M. G.
Clinical Cancer Research (1999)

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Phase I study of oral ZD1839 (Iressa™), a novel inhibitor of epidermal growth factor receptor tyrosine kinase (EGFR-TK): Evidence of good tolerability and activity

Meeting Abstract

Kris, M.; Ranson, M.; Ferry, D.; Hammond, L.; Averbuch, S.; Ochs, J.; Rowinsky, E.
Clinical Cancer Research (1999)

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Phase I trial of sequential paclitaxel and cisplatin in combination with the cyclin dependent kinase inhibitor flavopiridol (flavo) in patients with advanced solid tumors

Meeting Abstract

Schwartz, G. K.; Kaubisch, A.; Saltz, L.; Ilson, D.; O'Reilly, E.; Barazzuol, J.; Endres, S.; Stoltz, M.; Tong, W.; Kelsen, D. P.; more...
Clinical Cancer Research (1999)

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Induction of differentiation and apoptosis in human breast cancer cell lines by modified geldanamycin derivatives (17-AAG)

Meeting Abstract

Münster, P. N.; Zheng, F. F.; Srethapakdi, M.; Sausville, E.; Rosen, N.
Clinical Cancer Research (1999)

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Selective inhibition of cyclooxygenase-2 enhances mitomycin-C-induced apoptosis

Meeting Abstract

Hsueh, C. T.; Kelsen, D. P.; Schwartz, G. K.
Clinical Cancer Research (1999)

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Human pharmacokinetics of T138067, a novel antimicrotubule agent, given as a 3-hour infusion once every 21 to 28 days

Meeting Abstract

Berg, W.; Vongphrachanh, P.; Walling, J.; Wright, M.; Ye, Q.; Peterson, K.; Motzer, R.; Thoolen, M.; Timmermans, P.; Soignet, S.; more...
Clinical Cancer Research (1999)

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Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo

Meeting Abstract

Sirotnak, F. M.; Bornmann, W. G. B.; Miller, V. A.; Scher, H. I.; Kris, M. G.
Clinical Cancer Research (1999)

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