Synapse - Department of Medicine

Results (39622)

Phase 1 results of the WEE1 inhibitor, azenosertib, in combination with gemcitabine (gem) in adult and pediatric patients (pts) with relapsed or refractory (R/R) osteosarcoma

Meeting Abstract

Avutu, V.; Livingston, J. A.; Federman, N.; Cranmer, L. D.; Gaspar, N.; Toulmonde, M.; Pressey, J. G.; Brahmi, M.; Poklepovic, A. S.; Shi, Q.; more...
Journal of Clinical Oncology (2024)

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Phase I study of MCLA-145, a bispecific antibody targeting CD137 and PD-L1, in solid tumors, as monotherapy or in combination with pembrolizumab

Meeting Abstract

Kyi, C.; Van Dongen, M.; Rottey, S.; Bermejo, I. M.; Mittag, D.; Gouveia, D.; Bol, K.; Yan, C.; Joe, A. K.; Laus, G.; more...
Journal of Clinical Oncology (2024)

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Real-world (RW) risk of recurrence among patients (pts) diagnosed with stage II-III HR+/HER2-early breast cancer (EBC) treated with endocrine therapy (ET) in the US

Meeting Abstract

Razavi, P.; Ahmed, M.; Roush, A.; Parikh, R.; Hitchens, A.; Shen, S.; Safonov, A.; Jhaveri, K. L.; Robson, M. E.; Peacock, N. W.; more...
Journal of Clinical Oncology (2024)

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A phase II study evaluating the effect of IMNN-001 on second-look laparoscopy (SLL) when administered in combination with bevacizumab (BEV) and neoadjuvant chemotherapy (NACT) in patients newly diagnosed with advanced epithelial ovarian cancer (EOC)

Meeting Abstract

Jazaeri, A. A.; Grisham, R. N.; Gaillard, S.; How, J. A.; Hazard, S.; Musso, L.; Kyi, C.
Journal of Clinical Oncology (2024)

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First-line treatment preferences for advanced melanoma among oncologists and patients in the US: A discrete choice experiment

Meeting Abstract

Postow, M. A.; Burgos, G.; DeCongelio, M.; Palaia, J.; Ejzykowicz, F.; Patel, D.; Rosenblatt, L.; Modi, K.; Pittman, Z.; Honomichl, R.; more...
Journal of Clinical Oncology (2024)

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Immune-related adverse event prediction and influential factor identification

Meeting Abstract

Zhang, Y.; Lev-Ari, S.; Shah, N. J.; Gupta, S.; Zaemes, J. P.; Alaoui, A.; McGarvey, P.; Atkins, M. B.
Journal of Clinical Oncology (2024)

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TBCRC 058: A randomized phase II study of enzalutamide, enzalutamide with mifepristone, and treatment of physician's choice in patients with androgen receptor-positive metastatic triple-negative or estrogen receptor-low breast cancer (NCT06099769)

Meeting Abstract

Traina, T. A.; Chen, Y.; Khoury, K.; Rugo, H. S.; Mayer, E. L.; Carey, L. A.; Melisko, M. E.; Syldor, A.; Friedman, C.; Savoie, J.; more...
Journal of Clinical Oncology (2024)

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Biomarkers in a phase 1b study of investigational microbiome therapeutic SER-155 in adults undergoing allogeneic hematopoietic cell transplantation (allo-HCT)

Meeting Abstract

Ponce, D. M.; Pandian, S.; van den Brink, M. R. M.; Kosuri, S.; Khera, N.; DeFilipp, Z. M.; Tejura, B.; Lichter, D. I.; Chafee, M.; Bardhan, K.; more...
Journal of Clinical Oncology (2024)

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Updated quality-adjusted time without symptoms or toxicity (Q-TWiST) analysis of nivolumab plus chemotherapy versus chemotherapy alone as first-line (1L) treatment for advanced gastric cancer, gastroesophageal junction cancer, or esophageal adenocarcinoma (GC/GEJC/EAC): 4-year (yr) follow-up from CheckMate 649 (CM 649)

Meeting Abstract

Lin, D.; Quan, W.; Garretson, M.; Chirikov, V.; Chen, C.; Singh, P.; Davis, C.; Sugarman, R.
Journal of Clinical Oncology (2024)

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Glucagon-like peptide-1 (GLP-1) agonist use and weight change among patients with breast cancer

Meeting Abstract

Shen, S.; Liu, B.; Fanti, C.; Bromberg, M.; Chen, Y.; Chang, C.; Iyengar, N. M.
Journal of Clinical Oncology (2024)

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