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Results (22)

Characteristics of mismatch repair-deficient colon cancer in relation to mismatch repair protein loss, hypermethylation silencing, and constitutional and biallelic somatic mismatch repair gene pathogenic variants

Journal Article

Keshinro, A.; Ganesh, K.; Vanderbilt, C.; Firat, C.; Kim, J. K.; Chen, C. T.; Yaeger, R.; Segal, N. H.; Gonen, M.; Shia, J.; more...
Diseases of the Colon and Rectum (2023)

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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers

Journal Article

Chatila, W. K.; Walch, H.; Hechtman, J. F.; Moyer, S. M.; Sgambati, V.; Faleck, D. M.; Srivastava, A.; Tang, L.; Benhamida, J.; Ismailgeci, D.; more...
Nature Communications (2023)

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Integrative analysis of the contribution of genomic and clinical factors to worse clinical outcomes in non-Hispanic Black patients with colorectal cancer

Meeting Abstract

Walch, H.; Luthra, A.; Chatila, W. K.; Wu, F.; Chakravarty, D.; Chen, C. T.; Sood, R.; Omer, D. M.; Smith, J. J.; Schultz, N.; more...
Cancer Research (2022)

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Genomic profiling identifies differences in the distribution of APC mutations in non-Hispanic black and non-Hispanic white patients with colorectal cancer

Meeting Abstract

Walch, H.; Luthra, A.; Chatila, W.; Arora, K.; Chin, S.; Waters, M.; Smith, J. J.; Schultz, N.; Berger, M. F.; Ganesh, K.; more...
Cancer Research (2022)

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Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer

Journal Article

Chatila, W. K.; Kim, J. K.; Walch, H.; Marco, M. R.; Chen, C. T.; Wu, F.; Omer, D. M.; Khalil, D. N.; Ganesh, K.; Qu, X.; more...
Nature Medicine (2022)

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Transcriptomic profiling to identify subsets of immune hot locally advanced rectal adenocarcinomas with favorable outcomes after neoadjuvant treatment

Meeting Abstract

Sanchez Vega, F.; Chatila, W. K.; Kim, J. K.; Walch, H. S.; Marco, M.; Chen, C. T.; Wu, F.; Khalil, D.; Ganesh, K.; Qu, X.; more...
Journal of Clinical Oncology (2022)

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Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Journal Article

Nguyen, B.; Fong, C.; Luthra, A.; Smith, S. A.; DiNatale, R. G.; Nandakumar, S.; Walch, H.; Chatila, W. K.; Madupuri, R.; Kundra, R.; more...
Cell (2022)

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A comprehensive comparison of early-onset and average-onset colorectal cancers

Journal Article

Cercek, A.; Chatila, W. K.; Yaeger, R.; Walch, H.; Dos Santos Fernandes, G.; Krishnan, A.; Palmaira, L.; Maio, A.; Kemel, Y.; Srinivasan, P.; more...
JNCI: Journal of the National Cancer Institute (2021)

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Tumor-infiltrating lymphocytes, tumor mutational burden, and genetic alterations in microsatellite unstable, microsatellite stable, or mutant POLE/POLD1 colon cancer

Journal Article

Keshinro, A.; Vanderbilt, C.; Kim, J. K.; Firat, C.; Chen, C. T.; Yaeger, R.; Ganesh, K.; Segal, N. H.; Gonen, M.; Shia, J.; more...
JCO Precision Oncology (2021)

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Phase II single-arm study of durvalumab and tremelimumab with concurrent radiotherapy in patients with mismatch repair-proficient metastatic colorectal cancer

Journal Article

Segal, N. H.; Cercek, A.; Ku, G.; Wu, A. J.; Rimner, A.; Khalil, D. N.; Reidy-Lagunes, D.; Cuaron, J.; Yang, T. J.; Weiser, M. R.; more...
Clinical Cancer Research (2021)

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