Evaluation of association between degree of background parenchymal enhancement on MRI and breast cancer subtype Journal Article


Authors: Ha, R.; Mango, V.; Al-Khalili, R.; Mema, E.; Friedlander, L.; Desperito, E.; Wynn, R. T.
Article Title: Evaluation of association between degree of background parenchymal enhancement on MRI and breast cancer subtype
Abstract: Purpose: Evaluate possible association between BPE and breast cancer tumor type/prognostic markers. Methods: IRB approved retrospective study from 1/2010–1/2014 identified 328 patients who had breast MRI and available clinical/pathology data. BPE was categorized according to BI-RADS. The association between BPE and breast cancer molecular subtype/prognostic factors was evaluated. Results: No significant association was present between high BPE and the following: HER2+ tumors, basal tumors, tumors with axillary nodal disease, high nuclear grade tumors, high Ki-67 index tumors or larger tumors. Conclusion: Patients with high BPE may be at increased risk for breast cancer but not necessarily for those cancer subtypes with a poor prognosis. © 2018
Keywords: breast cancer risk; molecular subtype; bpe
Journal Title: Clinical Imaging
Volume: 51
ISSN: 0899-7071
Publisher: Elsevier Inc.  
Date Published: 2018-09-01
Start Page: 307
End Page: 310
Language: English
DOI: 10.1016/j.clinimag.2018.05.008
PROVIDER: scopus
PUBMED: 29945057
DOI/URL:
Notes: Article -- Export Date: 1 August 2018 -- Source: Scopus
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  1. Victoria Lee Mango
    14 Mango