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Results (54)

Allogeneic CAR T cells with regulated NEF expression display immune evasion and optimized signaling

Meeting Abstract

Perica, K.; Mansilla-Soto, J.; Kotchetkov, I.; Sadelain, M.
Molecular Therapy (2023)

Disruption of H3K9me3-mediated gene silencing augments CAR T cell functional persistence

Meeting Abstract

Jain, N.; Zhao, Z.; Koche, R.; Gozlan, Y.; Brocks, D.; Raveh-Sadka, T.; Wells, D.; Dobrin, A.; Shi, Y.; Lopez, M.; more...
Molecular Therapy (2022)

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Globin vector regulatory elements are active in early hematopoietic progenitor cells

Journal Article

Cabriolu, A.; Odak, A.; Zamparo, L.; Yuan, H.; Leslie, C. S.; Sadelain, M.
Molecular Therapy (2022)

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ADCLEC.syn1 is a novel combinatorial CAR platform for enhanced therapeutic index in AML

Meeting Abstract

Haubner, S.; Mansilla-Soto, J.; Nataraj, S.; Park, J.; Wang, X.; Rivière, I.; Sadelain, M.
Molecular Therapy (2021)

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CAR design and expression determine hyper-proliferative states in TET2 deficient T cells

Meeting Abstract

Jain, N.; Zhao, Z.; Iyer, A.; Lopez, M.; Feucht, J.; Koche, R.; Yang, J.; Zhan, Y.; Sadelain, M.
Molecular Therapy (2021)

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Establishing cGMP manufacturing of CRISPR/Cas9-edited human CAR T cells

Meeting Abstract

Wang, X.; Zabierowski, S. E.; Wu, M.; Zhu, M.; Del Casale, C.; Eyquem, J. E.; Mansilla-Soto, J.; Sadelain, M.; Riviere, I.
Molecular Therapy (2020)

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Co-targeting CD38 with a chimeric costimulatory receptor enhances adoptive T cell therapy for hematological malignancies

Meeting Abstract

Katsarou, A.; Sjostrand, M. L.; Nianias, A.; Poels, R.; Zweegman, S.; Mutis, T.; Sadelain, M.; Groen, R. W. J.; Themeli, M.
Molecular Therapy (2020)

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Novel genomic safe harbors for effective CAR T cell engineering

Meeting Abstract

Odak, A.; Yuan, H.; Mansilla-Soto, J.; Eyquem, J.; Vedantam, P.; Leslie, C.; Sadelain, M.
Molecular Therapy (2019)

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CAR-T cell manufacturing with CliniMACS Prodigy

Meeting Abstract

Wang, X.; Stefanski, J.; Chaudhari, J.; Hall, M.; Thummar, K.; Zhao, Z.; Sadelain, M.; Riviere, I.
Molecular Therapy (2019)

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Establishing cGMP manufacturing of CRISPR/Cas9-edited human CAR T cells

Meeting Abstract

Zabierowski, S.; Eyquem, J.; Mansilla-Soto, J.; Feucht, J.; Wang, X.; Riviere, I.; Sadelain, M.
Molecular Therapy (2019)

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