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Results (70)

Evaluation of Miltenyi ExpAct and TransAct CD3/28 beads for CAR-T cell manufacturing

Meeting Abstract

Wang, X.; Qu, J.; Stefanski, J.; Borquez-Ojeda, O.; Hack, A.; He, Q.; Wasielewska, T.; Du, F.; Sadelain, M.; Rivière, I.
Molecular Therapy (2016)

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One-step generation of universal CAR T cells

Meeting Abstract

Eyquem, J.; Mansilla-Soto, J.; Odak, A.; Sadelain, M.
Molecular Therapy (2016)

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Phase I clinical trial of autologous CD19-targeted 19-28z CAR T cells in adult patients with Relapsed or refractory B-ALL

Meeting Abstract

Park, J. H.; Riviere, I.; Wang, X. Y.; Bernal, Y.; Halton, E.; Quintanilla, H.; Curran, K.; Sauter, C.; Sadelain, M.; Brentjens, R. J.
Molecular Therapy (2015)

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CD19-targeted CAR T cells "armored" to secrete IL-12 demonstrate superior efficacy against B cell acute lymphoblastic leukemia and resist treg immunosuppression

Meeting Abstract

Chang, P. S.; Lee, J. C.; Koneru, M.; Brentjens, R. J.
Molecular Therapy (2015)

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Repair of the sickle-cell disease mutation in human stem cells using CRISPR/Cas9 and single-stranded oligodeoxynucleotides

Meeting Abstract

Mansilla-Soto, J.; Leyfman, Y.; Sadelain, M.
Molecular Therapy (2015)

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Activation signals from CD19-CAR permit NFAT-controlled inducible expression of transgenes in PBMCs

Meeting Abstract

Uchibori, R.; Teruya, T.; Ninomiya, S.; Ido, H.; Tsukahara, T.; Ohmine, K.; Urabe, M.; Saga, Y.; Kume, A.; Mizukami, H.; more...
Molecular Therapy (2015)

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Optimal activation of both CD28 and 4-1BB in CAR-targeted T cells results in enhanced tumor eradication

Meeting Abstract

Zhao, Z.; Van Der Stegen, S. J. C.; Condomines, M.; Perna, F.; Gunset, G.; Plotkin, J.; Sadelain, M.
Molecular Therapy (2015)

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ASGCT and JSGT joint position statement on human genomic editing

Journal Article

Friedmann, T.; Jonlin, E. C.; King, N. M. P.; Torbett, B. E.; Wivel, N. A.; Kaneda, Y.; Sadelain, M.
Molecular Therapy (2015)

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Genome editing technologies: Defining a path to clinic

Journal Article

Corrigan-Curay, J.; O'Reilly, M.; Kohn, D. B.; Cannon, P. M.; Bao, G.; Bushman, F. D.; Carroll, D.; Cathomen, T.; Joung, J. K.; Roth, D.; more...
Molecular Therapy (2015)

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Enhancing antitumor efficacy of chimeric antigen receptor T cells through constitutive CD40L expression

Journal Article

Curran, K. J.; Seinstra, B. A.; Nikhamin, Y.; Yeh, R.; Usachenko, Y.; van Leeuwen, D. G.; Purdon, T.; Pegram, H. J.; Brentjens, R. J.
Molecular Therapy (2015)

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