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Results (17)

A phase I trial for the treatment of purine analog-refractory chronic lymphocytic leukemia using autologous T cells genetically targeted to the B cell specific antigen CD19

Meeting Abstract

Brentjens, R. J.; Hollyman, D.; Weiss, M.; Stefanski, J.; Przybylowski, M.; Bartido, S.; Borquez-Ojeda, O.; Taylor, C.; Heaney, M.; Riviere, I.; more...
Journal of Clinical Oncology (2008)

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Strategies for therapeutic peptide delivery by mesenchymal stem cells

Meeting Abstract

Zhang, X. Y.; To, L.; Reiser, J.; Hemenway, C. S.; Sadelain, M. W.; La Russa, V. F.
Blood (2008)

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Off-the-shelf tumor immunotherapy with genetically enhanced allogeneic T-cell precursors

Meeting Abstract

Zakrzewski, J. L.; Suh, D.; Markley, J. C.; Smith, O. M.; King, C.; Goldberg, G.; Jenq, R.; Holland, A. M.; Grubin, J.; Cabrera-Perez, J.; more...
Biology of Blood and Marrow Transplantation (2008)

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Transcriptional and post transcriptional gene regulation in stem cell-based gene therapy

Meeting Abstract

Sadelain, M.
Blood Cells, Molecules, and Diseases (2008)

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MicroRNA regulation directs lineage- and developmental stage-specific transgene expression in hematopoietic stem cell progeny

Meeting Abstract

Papapetrou, E.; Kovalovsky, D.; Beloeil, L.; Sant'angelo, D.; Sadelain, M.
Blood Cells, Molecules, and Diseases (2008)

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Optimization of the beta-globin LCR and promoter elements for lentiviral vector-encoded the beta-globin transgene expression in beta-thalassemic mice

Meeting Abstract

Lisowski, L.; Sadelain, M.
Blood Cells, Molecules, and Diseases (2008)

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Tumor-targeted human CD4(+) CD25(hi) regulatory T cells effectively inhibit T cell-mediated rejection of CD19(+) tumors in an in vivo xenotransplant tumor model

Meeting Abstract

Lee, J.; Sadelain, M.; Brentjens, R. J.
Blood (2008)

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IL-15 augments in-vitro expansion and functional activity of antigen-specific effector memory T-cells (T(EM)) while co-expression of IL-15 and IL-15 R alpha on antigen presenting cells also promotes expansion of central memory T-cells (T(CM))