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Results (68)

Allogeneic CAR T cells with regulated NEF expression display immune evasion and optimized signaling

Meeting Abstract

Perica, K.; Mansilla-Soto, J.; Kotchetkov, I.; Sadelain, M.
Molecular Therapy (2023)

Disruption of H3K9me3-mediated gene silencing augments CAR T cell functional persistence

Meeting Abstract

Jain, N.; Zhao, Z.; Koche, R.; Gozlan, Y.; Brocks, D.; Raveh-Sadka, T.; Wells, D.; Dobrin, A.; Shi, Y.; Lopez, M.; more...
Molecular Therapy (2022)

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Globin vector regulatory elements are active in early hematopoietic progenitor cells

Journal Article

Cabriolu, A.; Odak, A.; Zamparo, L.; Yuan, H.; Leslie, C. S.; Sadelain, M.
Molecular Therapy (2022)

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Incorporation of bacterial immunoevasins to protect cell therapies from host antibody-mediated immune rejection

Journal Article

Peraro, L.; Bourne, C. M.; Dacek, M. M.; Akalin, E.; Park, J. H.; Smith, E. L.; Scheinberg, D. A.
Molecular Therapy (2021)

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Mechanisms of adoptive T cell micropharmacies

Meeting Abstract

Bourne, C. M.; Dacek, M. M.; Bah, M. A.; Romero-Pichardo, J.; Gardner, T. J.; Lee, P.; Tan, D.; Scheinberg, D. A.
Molecular Therapy (2021)

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ADCLEC.syn1 is a novel combinatorial CAR platform for enhanced therapeutic index in AML

Meeting Abstract

Haubner, S.; Mansilla-Soto, J.; Nataraj, S.; Park, J.; Wang, X.; Rivière, I.; Sadelain, M.
Molecular Therapy (2021)

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CAR design and expression determine hyper-proliferative states in TET2 deficient T cells

Meeting Abstract

Jain, N.; Zhao, Z.; Iyer, A.; Lopez, M.; Feucht, J.; Koche, R.; Yang, J.; Zhan, Y.; Sadelain, M.
Molecular Therapy (2021)

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Mechanisms of adoptive T cell micropharmacies

Meeting Abstract

Bourne, C.; Gardner, T.; Romero-Pichardo, J.; Lee, P.; Dacek, M.; Tan, D.; Scheinberg, D.
Molecular Therapy (2020)

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Establishing cGMP manufacturing of CRISPR/Cas9-edited human CAR T cells

Meeting Abstract

Wang, X.; Zabierowski, S. E.; Wu, M.; Zhu, M.; Del Casale, C.; Eyquem, J. E.; Mansilla-Soto, J.; Sadelain, M.; Riviere, I.
Molecular Therapy (2020)

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Co-targeting CD38 with a chimeric costimulatory receptor enhances adoptive T cell therapy for hematological malignancies

Meeting Abstract

Katsarou, A.; Sjostrand, M. L.; Nianias, A.; Poels, R.; Zweegman, S.; Mutis, T.; Sadelain, M.; Groen, R. W. J.; Themeli, M.
Molecular Therapy (2020)

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