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  • Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
    Journal Article

    Rojas, L. A.; Sethna, Z.; Soares, K. C.; Olcese, C.; Pang, N.; Patterson, E.; Lihm, J.; Ceglia, N.; Guasp, P.; Chu, A.; more...
    Nature (2023)

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  • TET2 guards against unchecked BATF3-induced CAR T cell expansion
    Journal Article

    Jain, N.; Zhao, Z.; Feucht, J.; Koche, R.; Iyer, A.; Dobrin, A.; Mansilla-Soto, J.; Yang, J.; Zhan, Y.; Lopez, M.; more...
    Nature (2023)

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  • Neoantigen quality predicts immunoediting in survivors of pancreatic cancer
    Journal Article

    Łuksza, M.; Sethna, Z. M.; Rojas, L. A.; Lihm, J.; Bravi, B.; Elhanati, Y.; Soares, K.; Amisaki, M.; Dobrin, A.; Hoyos, D.; more...
    Nature (2022)

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  • Anatomic position determines oncogenic specificity in melanoma
    Journal Article

    Weiss, J. M.; Hunter, M. V.; Cruz, N. M.; Baggiolini, A.; Tagore, M.; Ma, Y.; Misale, S.; Marasco, M.; Simon-Vermot, T.; Campbell, N. R.; more...
    Nature (2022)

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  • CTLA-4 blockade drives loss of T(reg) stability in glycolysis-low tumours
    Journal Article

    Zappasodi, R.; Serganova, I.; Cohen, I. J.; Maeda, M.; Shindo, M.; Senbabaoglu, Y.; Watson, M. J.; Leftin, A.; Maniyar, R.; Verma, S.; more...
    Nature (2021)

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  • The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
    Journal Article

    Hur, J. Y.; Frost, G. R.; Wu, X.; Crump, C.; Pan, S. J.; Wong, E.; Barros, M.; Li, T.; Nie, P.; Zhai, Y.; more...
    Nature (2020)

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  • Senolytic CAR T cells reverse senescence-associated pathologies
    Journal Article

    Amor, C.; Feucht, J.; Leibold, J.; Ho, Y. J.; Zhu, C.; Alonso-Curbelo, D.; Mansilla-Soto, J.; Boyer, J. A.; Li, X.; Giavridis, T.; more...
    Nature (2020)

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  • CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
    Journal Article

    Hamieh, M.; Dobrin, A.; Cabriolu, A.; van der Stegen, S. J. C.; Giavridis, T.; Mansilla-Soto, J.; Eyquem, J.; Zhao, Z.; Whitlock, B. M.; Miele, M. M.; more...
    Nature (2019)

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  • Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
    Journal Article

    Eyquem, J.; Mansilla-Soto, J.; Giavridis, T.; Van Der Stegen, S. J. C.; Hamieh, M.; Cunanan, K. M.; Odak, A.; Gönen, M.; Sadelain, M.
    Nature (2017)

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  • A combinatorial strategy for treating KRAS-mutant lung cancer
    Journal Article

    Manchado, E.; Weissmueller, S.; Morris, J. P.; Chen, C. C.; Wullenkord, R.; Lujambio, A.; de Stanchina, E.; Poirier, J. T.; Gainor, J. F.; Corcoran, R. B.; more...
    Nature (2016)

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