Heart failure related to contemporary breast cancer treatment Journal Article
| Authors: | Durkin, M.; DeJesus, N. |
| Article Title: | Heart failure related to contemporary breast cancer treatment |
| Abstract: | This article addresses cardiotoxicity in patients with breast cancer who are treated with anthracyclines and/or anti-human epidermal growth factor 2 (HER2) therapy, namely doxorubicin and trastuzumab. Development of concise clinical guidelines for chemotherapy-induced heart failure is ongoing. Through identification of specific risk factors and clinical predictors of cardiotoxicity, clinicians are able to better understand and define effective monitoring strategies and optimize patient care. Close cardiac monitoring is recommended for patients throughout treatment with anthracyclines and anti-HER2 therapy. Pretreatment risk assessment with echocardiography and evaluation of cardiovascular risk factors aid in predicting the development of left ventricular (LV) dysfunction. Further clinical trials are needed to increase understanding and optimize treatment guidelines for LV dysfunction in patients taking anthracyclines or anti-HER2 therapy. © 2024 American Academy of Physician Associates. |
| Keywords: | heart left ventricle failure; breast cancer; breast neoplasms; heart failure; cardiotoxicity; breast tumor; trastuzumab; anthracycline; anthracyclines; ventricular dysfunction, left; anti-her2 therapy; humans; human; female; left ventricular dysfunction |
| Journal Title: | Journal of the American Academy of Physician Assistants |
| Volume: | 37 |
| Issue: | 4 |
| ISSN: | 1547-1896 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2024-04-01 |
| Start Page: | 29 |
| End Page: | 33 |
| Language: | English |
| DOI: | 10.1097/01.JAA.0001005640.41824.fe |
| PUBMED: | 38531031 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
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